# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4403723 | Binding | Binding affinity to GABA-A alpha1 (unknown origin) assessed as increase in induced current relative to control | Homo sapiens | 23 | ALA4402545 | single protein format | Scientific Literature | |
2. | ALA4403724 | Binding | Binding affinity to GABA-A alpha2 (unknown origin) assessed as increase in induced current relative to control | Homo sapiens | 23 | ALA4402545 | single protein format | Scientific Literature | |
3. | ALA4403725 | Binding | Binding affinity to GABA-A alpha3 (unknown origin) assessed as increase in induced current relative to control | Homo sapiens | 15 | ALA4402545 | single protein format | Scientific Literature | |
4. | ALA4403726 | Binding | Binding affinity to GABA-A alpha5 (unknown origin) assessed as increase in induced current relative to control | Homo sapiens | 15 | ALA4402545 | single protein format | Scientific Literature | |
5. | ALA4403735 | Binding | Displacement of [3H]-Ro15-1788 from human GABAA alpha1beta3gamma2 expressed in HEK293 cell membranes incubated for 40 or 90 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA4402545 | cell-based format | Scientific Literature | |
6. | ALA4403736 | Binding | Displacement of [3H]-Ro15-1788 from human GABAA alpha2beta3gamma2 expressed in HEK293 cell membranes incubated for 40 or 90 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA4402545 | cell-based format | Scientific Literature | |
7. | ALA4403737 | Binding | Displacement of [3H]-Ro15-1788 from human GABAA alpha3beta3gamma2 expressed in HEK293 cell membranes incubated for 40 or 90 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA4402545 | cell-based format | Scientific Literature | |
8. | ALA4403738 | Binding | Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 expressed in HEK293 cell membranes incubated for 40 or 90 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA4402545 | cell-based format | Scientific Literature | |
9. | ALA4403769 | Functional | In vivo receptor occupancy at GABAA receptor in po dosed Wistar rat brain assessed as brain concentration causing reduction in [3H]Flunitrazepam receptor labeling by scintillation counting method | Rattus norvegicus | 1 | ALA4402545 | organism-based format | Scientific Literature | |
10. | ALA4725212 | Toxicity | Incucyte cell viability with HEK293T | Homo sapiens | 1,713 | ALA4689842 | cell-based format | EUbOPEN Chemogenomic Library | |
11. | ALA4725213 | Toxicity | Incucyte cell viability with human fibroblast | Homo sapiens | 1,718 | ALA4689842 | cell-based format | EUbOPEN Chemogenomic Library | |
12. | ALA4725214 | Toxicity | Incucyte cell viability with U2OS | Homo sapiens | 1,712 | ALA4689842 | cell-based format | EUbOPEN Chemogenomic Library |