| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4364724 | Binding | Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysis | Homo sapiens | 15 | ALA4364247 | subcellular format | Scientific Literature | |
| 2. | ALA4364725 | Binding | Selectivity index, ratio of IC50 for human placental cytosolic fraction 17beta-HSD1 to IC50 for human placental microsomal fraction 17beta-HSD2 | Homo sapiens | 15 | ALA4364247 | assay format | Scientific Literature | |
| 3. | ALA4364727 | Binding | Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysis | Homo sapiens | 15 | ALA4364247 | assay format | Scientific Literature | |
| 4. | ALA4364728 | Binding | Inhibition of recombinant mouse 17beta-HSD1 expressed in HEK293 cells at 1 uM using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysis relative to control | Mus musculus | 6 | ALA4364247 | cell-based format | Scientific Literature | |
| 5. | ALA4364730 | ADME | Cytotoxicity against human HEK293 cells assessed as cell viability at 6.3 uM after 66 hrs by MTT assay | Homo sapiens | 1 | ALA4364247 | cell-based format | Scientific Literature | |
| 6. | ALA4364731 | Unassigned | Selectivity index, ratio of cytotoxicity against HEK293 cells to IC50 for human placental cytosolic fraction 17beta-HSD1 | 1 | ALA4364247 | cell-based format | Scientific Literature | ||
| 7. | ALA4364732 | ADME | Half life in human liver S9 fraction at 1 uM in presence of NADPH | Homo sapiens | 14 | ALA4364247 | subcellular format | Scientific Literature | |
| 8. | ALA4364733 | Physicochemical | Aqueous solubility of the compound in phosphate-buffered saline at pH 7.2 after 1 to 24 hrs | 11 | ALA4364247 | small-molecule physicochemical format | Scientific Literature |
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