# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4427987 | B | Agonist activity at human BRS3 expressed in CHOK1 cells measured after 1 hrs by IP-One HTRF assay | Homo sapiens | 20 | ALA4425194 | cell-based format | Scientific Literature | |
2. | ALA4427988 | B | Agonist activity at mouse BRS3 expressed in CHOK1 cells measured after 1 hrs by IP-One HTRF assay | Mus musculus | 20 | ALA4425194 | cell-based format | Scientific Literature | |
3. | ALA4427995 | P | Octanol-water distribution coefficient, log D of the compound in PBS buffer at pH 7.4 | 2 | ALA4425194 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4427997 | P | Solubility of the compound in JP1 at pH 1.2 | 2 | ALA4425194 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4427998 | P | Solubility of the compound in JP2 at pH 6.8 | 2 | ALA4425194 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4427999 | A | Fraction unbound in mouse plasma | Mus musculus | 2 | ALA4425194 | cell-free format | Scientific Literature | |
7. | ALA4428003 | A | Plasma concentration in halothane anesthetized dog at 3 mg/kg/ml, iv measured after 30 mins | Canis lupus familiaris | 2 | ALA4425194 | organism-based format | Scientific Literature | |
8. | ALA4428004 | A | Plasma concentration in halothane anesthetized dog at 3 mg/kg/ml, iv measured after 60 mins | Canis lupus familiaris | 2 | ALA4425194 | organism-based format | Scientific Literature | |
9. | ALA4428005 | A | Cmax in halothane anesthetized dog showing 100.9% increase in heart rate at 3 mg/kg/ml, iv measured after 30 mins | Canis lupus familiaris | 2 | ALA4425194 | organism-based format | Scientific Literature | |
10. | ALA4428006 | A | Cmax in halothane anesthetized dog not showing increase in heart rate at 3 mg/kg/ml, iv measured after 30 mins | Canis lupus familiaris | 2 | ALA4425194 | organism-based format | Scientific Literature |