# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4421085 | Binding | Inhibition of N-terminal 6x-His-tagged recombinant human SOS1 catalytic domain (residues 564 to 1049 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in 50 nM SOS1-mediated GDP/GTP nucleotide exchange upon 2 uM N-terminal-GST-tagged H-Ras (1 to 166 residues) by BODIPY-FL-GDP dissociation assay | Homo sapiens | 36 | ALA4420078 | assay format | Patent Bioactivity Data | |
2. | ALA4888485 | Functional | Primary screen in NF54 nanoGlo assay, in single point, at 2uM, 72h | Plasmodium falciparum | 147,432 | ALA4888484 | organism-based format | MMV Malaria HGL |