# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4325517 | Binding | Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured over 20 mins by amplex red reagent-based horseradish peroxidase-coupled fluorometric assay | Homo sapiens | 52 | ALA4321878 | cell-based format | Scientific Literature | |
2. | ALA4325518 | Binding | Selectivity ratio of IC50 for recombinant human microsomal MAOA expressed in baculovirus infected BTI insect cells to IC50 for recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells | Homo sapiens | 55 | ALA4321878 | cell-based format | Scientific Literature | |
3. | ALA4325519 | Binding | Inhibition of recombinant human microsomal MAOA expressed in baculovirus infected BTI insect cells assessed as residual activity at 100 uM using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured over 20 mins by amplex red reagent-based horseradish peroxidase-coupled fluorometric assay relative to control | Homo sapiens | 29 | ALA4321878 | cell-based format | Scientific Literature | |
4. | ALA4325522 | Binding | Irreversible inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells at 10 times IC50 using p-tyramine as substrate preincubated for 15 mins followed by 100 fold dilution and subsequent substrate addition and measured for 30 mins by amplex red reagent-based horseradish peroxidase-coupled fluorometric assay | Homo sapiens | 51 | ALA4321878 | cell-based format | Scientific Literature |