# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4367261 | Binding | Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins by spectrophotometric method | Homo sapiens | 87 | ALA4364294 | single protein format | Scientific Literature | |
2. | ALA4367262 | Binding | Inhibition of recombinant human IDO1 expressed in T-REx-293 cells assessed as reduction in kynurenine level measured after 16 hrs | Homo sapiens | 73 | ALA4364294 | cell-based format | Scientific Literature | |
3. | ALA4367264 | ADME | Inhibition of CYP3A4 (unknown origin) using midazolam as substrate | Homo sapiens | 32 | ALA4364294 | single protein format | Scientific Literature | |
4. | ALA4367265 | ADME | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 32 | ALA4364294 | single protein format | Scientific Literature | |
5. | ALA4367266 | ADME | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 32 | ALA4364294 | single protein format | Scientific Literature | |
6. | ALA4367267 | ADME | Inhibition of CYP2B6 (unknown origin) | Homo sapiens | 32 | ALA4364294 | single protein format | Scientific Literature | |
7. | ALA4367268 | ADME | Intrinsic clearance in human liver microsomes | Homo sapiens | 19 | ALA4364294 | microsome format | Scientific Literature | |
8. | ALA4367272 | Binding | Inhibition of human ERG | Homo sapiens | 18 | ALA4364294 | single protein format | Scientific Literature | |
9. | ALA4367358 | ADME | Protein binding in plasma (unknown origin) assessed as unbound fraction | Not specified | 18 | ALA4364294 | cell-free format | Scientific Literature |