# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4353488 | Binding | Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells at 1 uM using Poly (4:1 Glu, Tyr) peptide substrate incubated for 60 mins by ADP-Glo assay relative to control | Homo sapiens | 23 | ALA4350989 | cell-based format | Scientific Literature | |
2. | ALA4353489 | Functional | Antiproliferative activity against human HCT116 cells overexpressing FAK assessed as reduction in cell viability after 72 hrs by MTS assay | Homo sapiens | 28 | ALA4350989 | cell-based format | Scientific Literature | |
3. | ALA4353490 | Functional | Antiproliferative activity against human PC3 cells overexpressing FAK assessed as reduction in cell viability after 72 hrs by MTS assay | Homo sapiens | 28 | ALA4350989 | cell-based format | Scientific Literature | |
4. | ALA4353491 | Functional | Antiproliferative activity against human U87MG cells overexpressing FAK assessed as reduction in cell viability after 72 hrs by MTS assay | Homo sapiens | 28 | ALA4350989 | cell-based format | Scientific Literature | |
5. | ALA4353492 | Functional | Antiproliferative activity against human MCF7 cells overexpressing FAK assessed as reduction in cell viability after 72 hrs by MTS assay | Homo sapiens | 28 | ALA4350989 | cell-based format | Scientific Literature |