# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4363567 | Functional | Antiviral activity against DENV-2 infected in human A549 or Mesocricetus auratus BHK21 cells preincubated for 30 mins further incubated for 1 hr followed by replacement of fresh medium containing compounds and measured at 8 hrs post infection by renilla luciferase assay | dengue virus type 2 | 30 | ALA4359909 | organism-based format | Scientific Literature | |
2. | ALA4363568 | ADME | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 30 | ALA4359909 | cell-based format | Scientific Literature | |
3. | ALA4363569 | Toxicity | Selectivity index, ratio of CC50 for human A549 or Mesocricetus auratus BHK21 cells to EC50 for antiviral activity against DENV-2 infected in A549or Mesocricetus auratus BHK21 cells | 30 | ALA4359909 | assay format | Scientific Literature | ||
4. | ALA5109274 | Functional | Antiviral activity against DENV infected in human A549 cells assessed as inhibition of virus induced cytopathic effect pre-incubated with virus for 30 mins followed by infection with cells measured after 8 to 24 hrs by luciferase activity assay | Dengue virus | 6 | ALA5107980 | organism-based format | Scientific Literature | |
5. | ALA5109275 | Toxicity | Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 5 | ALA5107980 | cell-based format | Scientific Literature | |
6. | ALA5109276 | Toxicity | Selectivity Index, ratio of CC50 for human A549 cells to EC50 for antiviral activity against DENV infected in human A549 cells | 5 | ALA5107980 | cell-based format | Scientific Literature | ||
7. | ALA5109284 | Functional | Larvicidal activity against Aedes aegypti assessed as mortality measured upto 48 hrs | Aedes aegypti | 6 | ALA5107980 | organism-based format | Scientific Literature |