# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4387102 | Binding | Inverse agonist activity at human CB1 receptor expressed in CHOK1 cells co-expressing Galphaq16 assessed as apparent equilibrium constant after 90 secs by calcein-4 AM dye-based FLIPR assay | Homo sapiens | 63 | ALA4385641 | cell-based format | Scientific Literature | |
2. | ALA4387103 | Binding | Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes | Homo sapiens | 63 | ALA4385641 | cell-based format | Scientific Literature | |
3. | ALA4387104 | Binding | Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes | Homo sapiens | 63 | ALA4385641 | cell-based format | Scientific Literature | |
4. | ALA4387105 | Binding | Selectivity ratio of Ki for displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes to Ki for displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes | Homo sapiens | 63 | ALA4385641 | cell-based format | Scientific Literature | |
5. | ALA4387106 | ADME | Permeability across apical to basolateral side in MDCK-MDR1 cells at 10 uM incubated for 1 hr by mass spectrometric method | Canis lupus familiaris | 63 | ALA4385641 | cell-based format | Scientific Literature | |
6. | ALA4387110 | ADME | Cmax in C57BL6 mouse plasma at 0.3 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | ALA4385641 | organism-based format | Scientific Literature |