| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4417198 | Functional | Inhibition of LTB4 production in A23187-stimulated human neutrophils at 0.001 to 1000 microM incubated for 30 mins by ELISA | Homo sapiens | 2 | ALA4414660 | cell-based format | Scientific Literature | |
| 2. | ALA4417199 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring p-nitroanilide release using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay | Homo sapiens | 9 | ALA4414660 | cell-based format | Scientific Literature | |
| 3. | ALA4417201 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat for p-nitroanilide release at 0.1 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.8 +/- 0.03 /s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 4. | ALA4417202 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat for p-nitroanilide release at 0.5 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.8 +/- 0.03 /s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 5. | ALA4417203 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat for p-nitroanilide release at 1 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.8 +/- 0.03 /s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 6. | ALA4417204 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat for p-nitroanilide release at 5 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.8 +/- 0.03 /s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 7. | ALA4417205 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat for p-nitroanilide release at 10 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.8 +/- 0.03 /s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 8. | ALA4417206 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Km for p-nitroanilide release at 0.1 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.59 +/- 0.09 mM) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 9. | ALA4417207 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Km for p-nitroanilide release at 0.5 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.59 +/- 0.09 mM) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 10. | ALA4417208 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Km for p-nitroanilide release at 1 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.59 +/- 0.09 mM) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 11. | ALA4417209 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Km for p-nitroanilide release at 5 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.59 +/- 0.09 mM) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 12. | ALA4417210 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Km for p-nitroanilide release at 10 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.59 +/- 0.09 mM) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 13. | ALA4417211 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat/Km ratio for p-nitroanilide release at 0.1 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.13 /mM/s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 14. | ALA4417212 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat/Km ratio for p-nitroanilide release at 0.5 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.13 /mM/s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 15. | ALA4417213 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat/Km ratio for p-nitroanilide release at 1 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.13 /mM/s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 16. | ALA4417214 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat/Km ratio for p-nitroanilide release at 5 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.13 /mM/s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 17. | ALA4417215 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring Kcat/Km ratio for p-nitroanilide release at 10 uM using L-Alanine-p-nitroanilide incubated for 10 mins by UV plate reader based assay (Rvb = 1.13 /mM/s) | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 18. | ALA4417216 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring reciprocal allosteric coupling constant for hyperbolic mixed predominantly catalytic activation using L-Alanine-p-nitroanilide incubated for 10 mins by p-nitroanilide release detection based UV plate reader based assay | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 19. | ALA4417217 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring factor by which activator affects catalytic constant for hyperbolic mixed predominantly catalytic activation using L-Alanine-p-nitroanilide incubated for 10 mins by p-nitroanilide release detection based UV plate reader based assay | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature | |
| 20. | ALA4417218 | Binding | Activation of N-terminal (His)6 and Xpress-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as increase in aminopeptidase activity by measuring dissociation constant (KX) for hyperbolic mixed predominantly catalytic activation using L-Alanine-p-nitroanilide incubated for 10 mins by p-nitroanilide release detection based UV plate reader based assay | Homo sapiens | 5 | ALA4414660 | cell-based format | Scientific Literature |
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