| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4413198 | B | Inhibition of porcine PDK assessed as activation of pyruvate dehydrogenase complex measured after 3 mins | Sus scrofa | 12 | assay format | Scientific Literature | ||
| 2. | ALA4413199 | B | Inhibition of PDK in human NCI-H1975 cells assessed as reduction in PDH phosphorylation at 10 uM after 12 hrs by Western blot analysis | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 3. | ALA4413201 | B | Inhibition of PDK in human NCI-H1975 cells assessed as reduction in PDH phosphorylation at Ser293 residue at 10 uM by ELISA | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA4413203 | B | Inhibition of recombinant human His-tagged PDK1 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminescence assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 5. | ALA4413204 | B | Inhibition of recombinant human His-tagged PDK2 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminescence assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 6. | ALA4413205 | B | Inhibition of recombinant human His-tagged PDK3 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminescence assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 7. | ALA4413206 | B | Inhibition of recombinant human His-tagged PDK4 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminescence assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 8. | ALA4413207 | B | Inhibition of human HSP90 measured after 30 mins by fluorescence polarization assay | Homo sapiens | 4 | protein format | Scientific Literature | ||
| 9. | ALA4413208 | B | Binding affinity to recombinant human His-tagged PDK1 expressed in Escherichia coli by isothermal calorimetry | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 10. | ALA4413209 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA4413210 | F | Antiproliferative activity against human NCI-H1650 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4413211 | F | Antiproliferative activity against human NCI-H1975 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4413212 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA4413213 | F | Antiproliferative activity against human A375 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA4413214 | F | Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA4413215 | F | Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA4413216 | A | Antiproliferative activity against human BEAS2B cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA4413217 | A | Permeability across human Caco2 cells by liquid scintillation counting method | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA4413218 | F | Induction of apoptosis in human NCI-H1975 cells assessed as live cells at 0.5 uM after 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 92.7%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4413219 | F | Induction of apoptosis in human NCI-H1975 cells assessed as early apoptotic cells at 0.5 uM after 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.8%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!