| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4433579 | ADME | Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 11 | ALA4433208 | single protein format | Scientific Literature | |
| 2. | ALA4433580 | ADME | Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 11 | ALA4433208 | single protein format | Scientific Literature | |
| 3. | ALA4433581 | ADME | Inhibition of recombinant human carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 11 | ALA4433208 | single protein format | Scientific Literature | |
| 4. | ALA4433582 | ADME | Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 11 | ALA4433208 | single protein format | Scientific Literature | |
| 5. | ALA4433583 | ADME | Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 11 | ALA4433208 | single protein format | Scientific Literature | |
| 6. | ALA4433584 | Binding | Inhibition of Trypanosoma cruzi carbonic anhydrase preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Trypanosoma cruzi | 11 | ALA4433208 | assay format | Scientific Literature | |
| 7. | ALA4433585 | Binding | Inhibition of Leishmania donovani chagasi carbonic anhydrase preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Leishmania donovani chagasi | 11 | ALA4433208 | assay format | Scientific Literature | |
| 8. | ALA4433586 | Binding | Inhibition of Malassezia globosa carbonic anhydrase preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Malassezia globosa | 11 | ALA4433208 | assay format | Scientific Literature | |
| 9. | ALA4433587 | Binding | Inhibition of Cryptococcus neoformans carbonic anhydrase preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Cryptococcus neoformans | 11 | ALA4433208 | assay format | Scientific Literature | |
| 10. | ALA4433588 | Functional | Antitrypanosomal activity against Trypanosoma cruzi Dm28c epimastigotes after 48 hrs by resazurin dye based assay | Trypanosoma cruzi | 3 | ALA4433208 | organism-based format | Scientific Literature | |
| 11. | ALA4433589 | Functional | Antitrypanosomal activity against Trypanosoma cruzi Y epimastigotes resazurin dye based assay | Trypanosoma cruzi | 3 | ALA4433208 | organism-based format | Scientific Literature | |
| 12. | ALA4433590 | Functional | Antitrypanosomal activity against Trypanosoma cruzi Dm28c epimastigotes assessed as reduction in epimastigotes number after 48 hrs by resazurin dye based spectrophotometric method | Trypanosoma cruzi | 3 | ALA4433208 | organism-based format | Scientific Literature | |
| 13. | ALA4433591 | Functional | Antitrypanosomal activity against Trypanosoma cruzi Y epimastigotes assessed as reduction in epimastigotes resazurin dye based spectrophotometric method assay | Trypanosoma cruzi | 3 | ALA4433208 | organism-based format | Scientific Literature | |
| 14. | ALA4433592 | ADME | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Mus musculus | 4 | ALA4433208 | cell-based format | Scientific Literature | |
| 15. | ALA4433593 | Toxicity | Selectivity index, ratio of CC50 for mouse RAW264.7 cells to IC50 for Trypanosoma cruzi Dm28c epimastigotes | 3 | ALA4433208 | assay format | Scientific Literature | ||
| 16. | ALA4433594 | Toxicity | Selectivity index, ratio of CC50 for mouse RAW264.7 cells to IC50 for Trypanosoma cruzi Y epimastigotes | 3 | ALA4433208 | assay format | Scientific Literature | ||
| 17. | ALA4433595 | Functional | Antitrypanosomal activity against Trypanosoma cruzi Dm28c trypomastigotes infected in African green monkey Vero cells incubated for 24 hrs by luciferase-luminescence based assay | Trypanosoma cruzi | 3 | ALA4433208 | organism-based format | Scientific Literature | |
| 18. | ALA4433596 | Functional | Antitrypanosomal activity against Trypanosoma cruzi Dm28c intracellular amastigotes infected in African green monkey Vero cells incubated for 24 hrs by luciferase-luminescence based assay | Trypanosoma cruzi | 3 | ALA4433208 | organism-based format | Scientific Literature | |
| 19. | ALA4433597 | ADME | Cytotoxicity against African green monkey Vero cells 72 hrs by CellTiter-Glo assay | Chlorocebus sabaeus | 3 | ALA4433208 | cell-based format | Scientific Literature | |
| 20. | ALA4433598 | Toxicity | Selectivity index, ratio of CC50 for African green monkey Vero cells to IC50 for Trypanosoma cruzi Dm28c trypomastigotes infected in African green monkey Vero cells | 3 | ALA4433208 | assay format | Scientific Literature |
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