| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4356374 | Binding | Displacement of [3H]NAMH from human H3R expressed in HEK293T cells incubated for 2 hrs by microbeta scintillation counting analysis | Homo sapiens | 24 | ALA4354817 | cell-based format | Scientific Literature | |
| 2. | ALA4356375 | Functional | Agonist activity at human H3R expressed on HEK293T cells assessed as inhibition of forskolin-induced CRE-driven luciferase activity co-incubated with forskolin for 6 hrs and measured after 30 mins by CRE-luciferase reporter gene assay | Homo sapiens | 24 | ALA4354817 | assay format | Scientific Literature | |
| 3. | ALA4356376 | Functional | Intrinsic activity at human H3R expressed on HEK293T cells assessed as activation of forskolin-induced CRE-driven luciferase activity co-incubated with forskolin for 6 hrs and measured after 30 mins by CRE-luciferase reporter gene assay relative to histamine | Homo sapiens | 23 | ALA4354817 | assay format | Scientific Literature |
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