# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4307543 | Binding | Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after 30 min by scintillation counting method | Homo sapiens | 2 | ALA4304801 | single protein format | Scientific Literature | |
2. | ALA4307544 | Binding | Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 30 min by scintillation counting method | Homo sapiens | 2 | ALA4304801 | single protein format | Scientific Literature | |
3. | ALA4307545 | Binding | Selectivity ratio of IC50 for FDPS (unknown origin) to IC50 for GGDPS (unknown origin) | Homo sapiens | 2 | ALA4304801 | assay format | Scientific Literature | |
4. | ALA4307546 | Binding | Inhibition of GGPPs in human RPMI8226 cells assessed as disruption of Rap1a geranylgeranylation measured after 48 hrs by immunoblot analysis | Homo sapiens | 2 | ALA4304801 | cell-based format | Scientific Literature | |
5. | ALA4307547 | Binding | Inhibition of GGPPs in human RPMI8226 cells assessed as disruption of Rab geranylgeranylation by ELISA | Homo sapiens | 2 | ALA4304801 | cell-based format | Scientific Literature |