| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4312767 | Binding | Inhibition of ligand binding to mTORC1/mTORC2 in human HuT78 cells after 2 hrs by kinobead competition binding assay | Homo sapiens | 36 | ALA4311944 | cell-based format | Scientific Literature | |
| 2. | ALA4312768 | Binding | Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by HTRF assay | Homo sapiens | 36 | ALA4311944 | single protein format | Scientific Literature | |
| 3. | ALA4312769 | Binding | Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by HTRF assay | Homo sapiens | 36 | ALA4311944 | single protein format | Scientific Literature | |
| 4. | ALA4312789 | ADME | Intrinsic clearance in rat microsomes | Rattus norvegicus | 5 | ALA4311944 | microsome format | Scientific Literature | |
| 5. | ALA4312790 | ADME | Intrinsic clearance in human microsomes | Homo sapiens | 5 | ALA4311944 | microsome format | Scientific Literature | |
| 6. | ALA4312791 | Physicochemical | Kinetic solubility of the compound in pH 7.4 phosphate buffered saline measured after 1 hr | 36 | ALA4311944 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA4312792 | Physicochemical | Lipophilicity, logP of the compound by reversed phase column chromatography | 36 | ALA4311944 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA4312793 | Binding | Inhibition of PI3K/AKT/mTOR in human lung fibroblasts assessed as reduction in AKT phosphorylation at serine473 residue preincubated for 1 hr followed by PDGF-BB stimulation and measured after 10 mins by electrochemiluminescence method | Homo sapiens | 36 | ALA4311944 | assay format | Scientific Literature |
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