# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4392742 | Binding | Inhibition of recombinant human N-terminal GST-tagged BRAF V600E mutant catalytic domain (416 to 766 residues) expressed in baculovirus expression system using human His6-tagged MEK1 (K97R) as substrate preincubated for 20 mins followed by [33P-gamma]ATP addition and measured after 2 hrs by filter-binding assay | Homo sapiens | 15 | ALA4390702 | assay format | Scientific Literature | |
2. | ALA4392743 | Binding | Inhibition of recombinant full-length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Fluor-de-Lys as substrate measured after 10 mins by fluorescence assay | Homo sapiens | 14 | ALA4390702 | cell-based format | Scientific Literature | |
3. | ALA4392749 | Functional | Antiproliferative activity against human K562 cells measured after 48 hrs by MTT assay | Homo sapiens | 7 | ALA4390702 | cell-based format | Scientific Literature | |
4. | ALA4392750 | Functional | Antiproliferative activity against human MV4-11 cells measured after 48 hrs by MTT assay | Homo sapiens | 7 | ALA4390702 | cell-based format | Scientific Literature | |
5. | ALA4392751 | Functional | Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay | Homo sapiens | 7 | ALA4390702 | cell-based format | Scientific Literature | |
6. | ALA4392752 | Functional | Antiproliferative activity against human MDA-MB-468 cells measured after 48 hrs by MTT assay | Homo sapiens | 7 | ALA4390702 | cell-based format | Scientific Literature |