# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4355751 | A | Apparent permeability in pig LLC-PK1 cells transfected with MDR1 | Sus scrofa | 25 | cell-based format | Scientific Literature | ||
2. | ALA4355753 | A | Fraction unbound in human plasma at 2.5 uM by equilibrium dialysis | Homo sapiens | 11 | cell-free format | Scientific Literature | ||
3. | ALA4355754 | B | Inhibition of recombinant human OGA | Homo sapiens | 48 | single protein format | Scientific Literature | ||
4. | ALA4355755 | B | Inhibition of OGA in rat PC12 cells assessed as OGlcNAcylated protein level incubated for 24 hrs by ELISA | Rattus norvegicus | 25 | cell-based format | Scientific Literature | ||
5. | ALA4355756 | B | Inhibition of human beta hexosaminidase assessed as inhibitory constant using 4-methylumbelliferyl N-acetyl-beta-D-glucosaminide dihydrate as substrate measured every 60 sec for 45 mins by fluorescence spectrophotometry | Homo sapiens | 41 | single protein format | Scientific Literature | ||
6. | ALA4355757 | A | Fraction unbound in Wistar Han rat plasma at 2.5 uM by equilibrium dialysis | Rattus norvegicus | 11 | cell-free format | Scientific Literature | ||
7. | ALA4355759 | A | AUCN in Wistar Han rat at 3 mg/kg, po | Rattus norvegicus | 14 | organism-based format | Scientific Literature | ||
8. | ALA4355761 | A | Clearance in Wistar Han rat at 1 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
9. | ALA4355763 | A | Half life in Wistar Han rat at 1 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
10. | ALA4355766 | A | Volume of distribution at steady state in Wistar Han rat at 1 mg/kg, iv or 3 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
11. | ALA4355768 | A | Oral bioavailability in Wistar Han rat at 3 mg/kg | Rattus norvegicus | 14 | organism-based format | Scientific Literature |