#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4324283	ADME	Clearance in human liver microsomes measured per mg of protein	Homo sapiens	7	ALA4321846	microsome format	Scientific Literature
2.	ALA4324284	Binding	Inhibition of MEK U911-activated ERK2 (unknown origin) using ERKtide as substrate preincubated for 20 mins followed by substrate addition in presence of ATP at Km concentration after 20 mins by rapidfire mass spectrometry analysis	Homo sapiens	8	ALA4321846	single protein format	Scientific Literature
3.	ALA4324285	Binding	Inhibition of MEK U911-activated ERK2 (unknown origin) using ERKtide as substrate preincubated for 20 mins followed by substrate addition in presence of 1 mM ATP after 10 mins by rapidfire mass spectrometry analysis	Homo sapiens	8	ALA4321846	single protein format	Scientific Literature
4.	ALA4324286	Binding	Inhibition of ERK1/2 in human A375 cells assessed as inhibition of ERK phosphorylation after 2 hrs	Homo sapiens	11	ALA4321846	cell-based format	Scientific Literature
5.	ALA4324287	Binding	Inhibition of ERK1/2 in human A375 cells assessed as inhibition of RSK phosphorylation after 2 hrs	Homo sapiens	11	ALA4321846	cell-based format	Scientific Literature
6.	ALA4324288	Physicochemical	1-Octanol-PBS buffer distribution coefficient, log D of compound at pH 7.4		8	ALA4321846	small-molecule physicochemical format	Scientific Literature
7.	ALA4324289	Physicochemical	Solubility of compound in PBS at pH 7.4 after 24 hrs		8	ALA4321846	small-molecule physicochemical format	Scientific Literature
8.	ALA4324290	Binding	Inhibition of recombinant human GST-tagged c-RAF1 Y340D/Y341D mutant catalytic domain expressed in baculovirus expression system at 1 uM relative to control	Homo sapiens	1	ALA4321846	assay format	Scientific Literature
9.	ALA4324291	Binding	Inhibition of recombinant full length GST-tagged human BRAF1 expressed in baculovirus expression system at 1 uM relative to control	Homo sapiens	1	ALA4321846	assay format	Scientific Literature
10.	ALA4324292	Binding	Inhibition of recombinant full length his-tagged human MEK2 expressed in baculovirus expression system at 1 uM relative to control	Homo sapiens	1	ALA4321846	assay format	Scientific Literature
11.	ALA4324293	Binding	Inhibition of recombinant full length His-tagged human MEK1 expressed in baculovirus expression system at 1 uM relative to control	Homo sapiens	1	ALA4321846	assay format	Scientific Literature
12.	ALA4324294	ADME	Intrinsic clearance in rat hepatocytes measured per million of cells	Rattus norvegicus	5	ALA4321846	cell-based format	Scientific Literature
13.	ALA4324295	ADME	Intrinsic clearance in human hepatocytes measured per million of cells	Homo sapiens	5	ALA4321846	cell-based format	Scientific Literature
14.	ALA4324296	ADME	Apparent permeability across apical to basolateral side in human Caco2 cells	Homo sapiens	5	ALA4321846	cell-based format	Scientific Literature
15.	ALA4324297	Binding	Inhibition of human ERG	Homo sapiens	5	ALA4321846	single protein format	Scientific Literature
16.	ALA4324298	Binding	Binding affinity to recombinant human N-terminal 4xFLAG-tagged/C-terminal His8-fused ERK7 N-terminal domain (M1 to R354 residues) expressed in Sf9 insect cells	Homo sapiens	1	ALA4321846	cell-based format	Scientific Literature
17.	ALA4324299	Binding	Inhibition of recombinant full length human His-tagged ARK5 expressed in baculovirus expression system	Homo sapiens	1	ALA4321846	assay format	Scientific Literature
18.	ALA4324300	Binding	Inhibition of recombinant full length human GST/His-tagged CDK5/p25 expressed in baculovirus expression system	Homo sapiens	1	ALA4321846	assay format	Scientific Literature
19.	ALA4324301	Binding	Inhibition of recombinant full length human His-tagged CDK5/p35 expressed in baculovirus expression system	Homo sapiens	1	ALA4321846	assay format	Scientific Literature
20.	ALA4324302	Binding	Binding affinity to recombinant human GST-tagged inactive CDK5	Homo sapiens	1	ALA4321846	single protein format	Scientific Literature