| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4339112 | B | Inhibition of human N-terminal GST-tagged IDO1 expressed in Escherichia coli Rosetta(DE3) pLysS using L-tryptophan as substrate measured after 1 hr by fluorescence assay | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 2. | ALA4339113 | B | Inhibition of IDO1 in interferon-gamma-induced human SKOV3 cells assessed as N-formylkynurenine formation using L-tryptophan as substrate measured after 24 hrs by fluorescence assay | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 3. | ALA4339116 | A | Stability assessed as recombinant UGT1A9 (unknown origin) mediated compound glucuronidation by measuring half-life at 1 uM incubated in water bath by shaking at 37 degree C measured upto 60 mins in presence of UDPGA by LC-MS/MS analysis | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 4. | ALA4339117 | A | Drug metabolism in human hepatocytes assessed as parent compound remaining by measuring glucuronide formation at 5 uM measured at 120 mins by UPLC-PDA/MS analysis | Homo sapiens | 16 | cell-based format | Scientific Literature |
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