| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4478761 | B | Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF assay | Homo sapiens | 29 | assay format | Scientific Literature | ||
| 2. | ALA4478762 | B | Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assay | Homo sapiens | 28 | assay format | Scientific Literature | ||
| 3. | ALA4478763 | B | Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assay | Homo sapiens | 28 | assay format | Scientific Literature | ||
| 4. | ALA4478764 | B | Inhibition of human Gst-tagged TYK2 ( 871 to 1187 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assay | Homo sapiens | 28 | assay format | Scientific Literature | ||
| 5. | ALA4478765 | P | Distribution coefficient, logD of the compound at pH 7.4 | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4478767 | B | Inhibition of JAK in human B lymphocyte cells assessed as suppression of IL4-induced STAT6 phosphorylation preincubated for 1 hr followed by IL4 addition measured after 41/2 to 5 hrs by STAT6 reporter gene assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 7. | ALA4478768 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 4 | microsome format | Scientific Literature | ||
| 8. | ALA4478769 | B | Binding affinity to human ERG | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 9. | ALA4478770 | F | Phototoxicity in mouse 3T3 cells assessed as reduction in cell viability preincubated for 1 hr followed by UV irradiation measured after 24 hrs by Vital dye Neutral Red assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4478771 | T | Toxicity in mouse 3T3 cells assessed as reduction in cell viability preincubated for 1 hr followed by incubation in dark measured after 24 hrs by Vital dye Neutral Red assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4478772 | U | Ratio of IC50 for mouse 3T3 cells in absence of uv radiation to IC50 for mouse 3T3 cells in presence of uv radiation | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4478773 | P | Half life of the compound in presence of simulated outdoor light after 6 hrs by LCMS analysis | 3 | small-molecule physicochemical format | Scientific Literature |
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