| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4392265 | B | Inhibition of recombinant rat C-terminal His-tagged soluble form of CD73 expressed in baculovirus infected Sf9 insect cells using [2,8-3H]AMP as substrate measured after 25 mins by scintillation counting method | Rattus norvegicus | 51 | cell-based format | Scientific Literature | ||
| 2. | ALA4392266 | B | Inhibition of recombinant rat C-terminal His-tagged soluble form of CD73 expressed in baculovirus infected Sf9 insect cells at 1 uM using [2,8-3H]AMP as substrate measured after 25 mins by scintillation counting method relative to control | Rattus norvegicus | 51 | cell-based format | Scientific Literature | ||
| 3. | ALA4392267 | B | Inhibition of recombinant human C-terminal His-tagged soluble form of CD73 expressed in baculovirus infected Sf9 insect cells using [2,8-3H]AMP as substrate measured after 25 mins by scintillation counting method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA4392268 | B | Inhibition of CD73 in human MDA-MB-231 cell membranes using [2,8-3H]AMP as substrate measured after 25 mins by scintillation counting method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA4392269 | F | Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as induction of calcium mobilization by calcium-4 dye based FLIPR assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4392271 | B | Displacement of 6-Amino-9-(2-carboxy-4-((6-(4-(4-(4-(4-(3-carboxy-6-(4-(trifluoromethyl)phenyl)-naphthalen-1-yl)phenyl)piperidin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)hexyl)carbamoyl)-phenyl)-3-iminio-5-sulfo-3H-xanthene-4-sulfonate from recombinant human P2Y14 receptor expressed in CHO cells preincubated for 30 mins followed by tracer addition and measured after 30 mins by flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4392273 | B | Inhibition of cytosolic nucleotidase in MaMel.65-CD73 cell cytosolic extract (unknown origin) at 100 uM using AMP as substrate preincubated for 5 mins followed by substrate addition and measured after 60 mins by malachite green oxalate dye based colorimetric method relative to control | Homo sapiens | 4 | assay format | Scientific Literature |
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