# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4379766 | Functional | Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production after 30 mins in presence of CP55940 at EC20 concentration by hit-hunter cAMP assay | Homo sapiens | 29 | ALA4376840 | cell-based format | Scientific Literature | |
2. | ALA4379767 | Functional | Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production after 30 mins in presence of CP55940 at EC20 concentration by hit-hunter cAMP assay relative to control | Homo sapiens | 29 | ALA4376840 | cell-based format | Scientific Literature | |
3. | ALA4379768 | Binding | Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced beta-arrestin2 recruitment after 90 mins in presence of CP55940 at EC20 concentration by pathhunter beta-arrestin assay | Homo sapiens | 29 | ALA4376840 | cell-based format | Scientific Literature | |
4. | ALA4379769 | Binding | Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced beta-arrestin2 recruitment after 90 mins in presence of CP55940 at EC20 concentration by pathhunter beta-arrestin assay relative to control | Homo sapiens | 29 | ALA4376840 | cell-based format | Scientific Literature | |
5. | ALA4672175 | Binding | Positive allosteric modulatory activity at human CB1 receptor expressed in CHO-K1 cells assessed as increase in CP55940-induced beta-arrestin recruitment preincubated 90 mins followed by CP55940 addition and measured after 60 mins by PathHunter assay relative to CP55940 | Homo sapiens | 41 | ALA4665860 | cell-based format | Scientific Literature | |
6. | ALA4672176 | Binding | Positive allosteric modulatory activity at human CB1 receptor expressed in CHO-K1 cells assessed as increase in CP55940-induced beta-arrestin recruitment preincubated 90 mins followed by CP55940 addition and measured after 60 mins by PathHunter assay | Homo sapiens | 41 | ALA4665860 | cell-based format | Scientific Literature | |
7. | ALA4672177 | Functional | Positive allosteric modulatory activity at human CB1 receptor expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production preincubated for 30 mins followed by CP55940 addition and measured after 60 mins by Hit-hunter assay relative to control | Homo sapiens | 41 | ALA4665860 | cell-based format | Scientific Literature | |
8. | ALA4672178 | Functional | Positive allosteric modulatory activity at human CB1 receptor expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production preincubated for 30 mins followed by CP55940 addition and measured after 60 mins by Hit-hunter assay | Homo sapiens | 41 | ALA4665860 | cell-based format | Scientific Literature |