| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4423288 | Physicochemical | Octanol-water partitioning co-efficient, log D of the compound at pH 7.4 by LC/MS/MS analysis | 52 | ALA4422622 | small-molecule physicochemical format | Scientific Literature | ||
| 2. | ALA4423290 | Binding | Displacement of [3H]-aldosterone to human mineralocorticoid receptor LBD by radiometric binding assay | Homo sapiens | 52 | ALA4422622 | single protein format | Scientific Literature | |
| 3. | ALA4423291 | Binding | Binding affinity to recombinant human GR LBD by fluormone GS red-fluorescence polarization assay | Homo sapiens | 47 | ALA4422622 | single protein format | Scientific Literature | |
| 4. | ALA4423293 | Binding | Antagonist activity at gal4-fused human mineralocorticoid receptor LBD expressed in UAS-MR-bla HEK293 cells by luciferase reporter gene assay | Homo sapiens | 52 | ALA4422622 | cell-based format | Scientific Literature | |
| 5. | ALA4423294 | Binding | Antagonist activity at human gal4-fused mineralocorticoid receptor LBD expressed in UAS-MR-bla HEK293 by luciferase reporter gene assay relative to control | Homo sapiens | 42 | ALA4422622 | assay format | Scientific Literature | |
| 6. | ALA4423296 | ADME | Apparent permeability in human Caco2 cells at 10 uM after 45 to 120 mins by LC/MS/MS analysis | Homo sapiens | 19 | ALA4422622 | cell-based format | Scientific Literature | |
| 7. | ALA4423297 | ADME | Intrinsic clearance in human hepatocytes assessed per million cells at 1 uM measured up to 120 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 30 | ALA4422622 | cell-based format | Scientific Literature |
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