# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4362824 | Functional | Induction of apoptosis in human HCT116 cells expressing wild type p53 assessed as live cells at 20 uM measured after 72 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 83.7 %) | Homo sapiens | 21 | ALA4359887 | cell-based format | Scientific Literature | |
2. | ALA4362825 | Functional | Induction of apoptosis in human HCT116 cells expressing wild type p53 assessed as early apoptotic cells expressing wild type p53 at 20 uM measured after 72 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 8.8 %) | Homo sapiens | 21 | ALA4359887 | cell-based format | Scientific Literature | |
3. | ALA4362826 | Functional | Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells expressing wild type p53 at 20 uM measured after 72 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 6.8 %) | Homo sapiens | 21 | ALA4359887 | cell-based format | Scientific Literature | |
4. | ALA4362827 | Functional | Induction of apoptosis in human HCT116 cells expressing wild type p53 assessed as necrotic cells at 20 uM measured after 72 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 0.7 %) | Homo sapiens | 21 | ALA4359887 | cell-based format | Scientific Literature |