# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4352686 | Binding | Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment at 1000 nM preincubated for 30 mins followed by CP55940 addition and measured after 90 to 180 mins by PathHunter assay relative to CP55940 | Homo sapiens | 11 | ALA4350967 | cell-based format | Scientific Literature | |
2. | ALA4352690 | Binding | Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment preincubated for 30 mins followed by CP55940 addition and measured after 90 to 180 mins by PathHunter assay | Homo sapiens | 12 | ALA4350967 | cell-based format | Scientific Literature | |
3. | ALA4352691 | ADME | Agonist activity at human CB1 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 30 mins by PathHunter assay | Homo sapiens | 12 | ALA4350967 | cell-based format | Scientific Literature | |
4. | ALA4352692 | Binding | Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment preincubated for 30 mins followed by CP55940 addition and measured after 90 to 180 mins by PathHunter assay relative to CP55940 | Homo sapiens | 12 | ALA4350967 | cell-based format | Scientific Literature | |
5. | ALA4352693 | ADME | Agonist activity at human CB1 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 30 mins by PathHunter assay relative to CP55940 | Homo sapiens | 12 | ALA4350967 | cell-based format | Scientific Literature | |
6. | ALA4352700 | Functional | Positive allosteric modulation of human Gi/Go-coupled CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production preincubated for 30 mins followed by CP55940 addition and measured after 30 to 60 mins by Hit-hunter assay | Homo sapiens | 4 | ALA4350967 | cell-based format | Scientific Literature | |
7. | ALA4352701 | ADME | Agonist activity at human Gi/Go-coupled CB1 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP production measured after 30 mins by Hit-hunter assay | Homo sapiens | 4 | ALA4350967 | cell-based format | Scientific Literature | |
8. | ALA4352702 | Functional | Positive allosteric modulation of human Gi/Go-coupled CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production preincubated for 30 mins followed by CP55940 addition and measured after 30 to 60 mins by Hit-hunter assay relative to CP55940 | Homo sapiens | 4 | ALA4350967 | cell-based format | Scientific Literature | |
9. | ALA4352703 | ADME | Agonist activity at human Gi/Go-coupled CB1 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP production measured after 30 mins by Hit-hunter assay relative to CP55940 | Homo sapiens | 4 | ALA4350967 | cell-based format | Scientific Literature | |
10. | ALA4352709 | Binding | Positive allosteric modulation of CB1 receptor in mouse brain membranes assessed as increase in [3H]CP55940 binding at 1 uM measured after 60 mins relative to control | Mus musculus | 4 | ALA4350967 | cell membrane format | Scientific Literature |