| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4385011 | F | Induction of apoptosis in human HL60 cells assessed as early apoptotic cells at 3 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 2.4%) | Homo sapiens | 1 | ALA4382264 | cell-based format | Scientific Literature | |
| 2. | ALA4385012 | F | Inhibition of alpha-MSH-stimulated melanogenesis in mouse B16F10 cells assessed as melanin content at 10 uM measured after 48 hrs relative to control | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
| 3. | ALA4385013 | F | Inhibition of alpha-MSH-stimulated melanogenesis in mouse B16F10 cells assessed as melanin content at 100 uM measured after 48 hrs relative to control | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
| 4. | ALA4385014 | A | Cytotoxicity against non-stimulated mouse B16F10 cells assessed as cell viability at 10 uM relative to control | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
| 5. | ALA4385015 | A | Cytotoxicity against non-stimulated mouse B16F10 cells assessed as cell viability at 100 uM relative to control | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
| 6. | ALA4385016 | U | Selectivity index, ratio of compound effect for cytotoxicity against non-stimulated mouse B16F10 cells assessed as cell viability at 10 uM to compound effect for inhibition of alpha-MSH-stimulated melanogenesis in mouse B16F10 cells assessed as melanin content at 10 uM | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
| 7. | ALA4385017 | U | Selectivity index, ratio of compound effect for cytotoxicity against non-stimulated mouse B16F10 cells assessed as cell viability at 100 uM to compound effect for inhibition of alpha-MSH-stimulated melanogenesis in mouse B16F10 cells assessed as melanin content at 100 uM | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
| 8. | ALA4385018 | F | Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
| 9. | ALA4385019 | F | Cytotoxicity against human AZ-521 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
| 10. | ALA4385020 | F | Cytotoxicity against human SKBR3 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
| 11. | ALA4385021 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
| 12. | ALA4385022 | A | Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
| 13. | ALA4385023 | U | Selectivity index, ratio of IC50 for human W138 cells to IC50 for human A549 cells | Homo sapiens | 5 | ALA4382264 | assay format | Scientific Literature | |
| 14. | ALA4385024 | F | Induction of apoptosis in human HL60 cells assessed as cell shrinkage at 0.3 to 3 uM after 24 hrs by Hoechst 33342 staining based fluorescence microscopic analysis | Homo sapiens | 1 | ALA4382264 | cell-based format | Scientific Literature | |
| 15. | ALA4385025 | F | Induction of apoptosis in human HL60 cells assessed as fragmentation of nuclei at 1 to 3 uM after 24 hrs by Hoechst 33342 staining based fluorescence microscopic analysis | Homo sapiens | 1 | ALA4382264 | cell-based format | Scientific Literature | |
| 16. | ALA4385026 | F | Induction of apoptosis in human HL60 cells assessed as chromatin condensation at 1 to 3 uM after 24 hrs by Hoechst 33342 staining based fluorescence microscopic analysis | Homo sapiens | 1 | ALA4382264 | cell-based format | Scientific Literature | |
| 17. | ALA4385027 | F | Induction of apoptosis in human HL60 cells assessed as late apoptotic cells at 3 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 3%) | Homo sapiens | 1 | ALA4382264 | cell-based format | Scientific Literature | |
| 18. | ALA4385028 | F | Induction of apoptosis in human HL60 cells assessed as early apoptotic cells at 3 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.8%) | Homo sapiens | 1 | ALA4382264 | cell-based format | Scientific Literature | |
| 19. | ALA4385029 | F | Induction of apoptosis in human HL60 cells assessed as late apoptotic cells at 3 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.9%) | Homo sapiens | 1 | ALA4382264 | cell-based format | Scientific Literature | |
| 20. | ALA4385030 | F | Induction of apoptosis in human HL60 cells assessed as increase in cleaved caspase-3 expression at 3 uM after 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4382264 | cell-based format | Scientific Literature |
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