The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4431051 B Inhibition of human Kv1.5 transfected in mouse LTK cells Homo sapiens 16 cell-based format Scientific Literature 2. ALA4431052 B Inhibition of human Kv1.5 transfected in mouse LTK cells at 0.3 uM Homo sapiens 12 cell-based format Scientific Literature 3. ALA4431053 B Inhibition of human ERG expressed in HEK293 cells by thallium flux assay Homo sapiens 16 cell-based format Scientific Literature 4. ALA4431054 A Stability in rat liver microsomes Rattus norvegicus 1 microsome format Scientific Literature 5. ALA4431055 A Clearance in Sprague-Dawley rat hemodynamic/VERP model at 2 mg/kg, iv Rattus norvegicus 2 organism-based format Scientific Literature 6. ALA4431056 A Volume of distribution at steady state in Sprague-Dawley rat hemodynamic/VERP model at 2 mg/kg, iv Rattus norvegicus 2 organism-based format Scientific Literature 7. ALA4431057 A Half life in Sprague-Dawley rat hemodynamic/VERP model at 2 mg/kg, iv Rattus norvegicus 2 organism-based format Scientific Literature 8. ALA4431058 A Half life in Sprague-Dawley rat hemodynamic/VERP model at 5 mg/kg, po Rattus norvegicus 2 organism-based format Scientific Literature 9. ALA4431059 A Oral bioavailability in Sprague-Dawley rat hemodynamic/VERP model at 5 mg/kg Rattus norvegicus 2 organism-based format Scientific Literature 10. ALA4431060 A Pro-arrhythmic activity in rat assessed as plasma concentration required to increase 98 +/- 3% ventricular effective refractory period at 10 mg/kg, iv as 10 mins infusion Rattus norvegicus 1 organism-based format Scientific Literature 11. ALA4431061 A Pro-arrhythmic activity in rat assessed as increase in ventricular effective refractory period at 10 mg/kg, iv as 10 mins infusion Rattus norvegicus 2 organism-based format Scientific Literature 12. ALA4431062 F Increase in atrial effective refractory period in rabbit at 3 mg/kg, iv as 30 mins infusion measured at 20 mins Oryctolagus cuniculus 2 organism-based format Scientific Literature 13. ALA4431063 A Plasma concentration in rabbit at 3 mg/kg, iv as 30 mins infusion Oryctolagus cuniculus 2 organism-based format Scientific Literature 14. ALA4431072 T Toxicity in rabbit assessed as change in systolic blood pressure at 3 mg/kg, iv as 30 mins infusion measured at 20 mins Oryctolagus cuniculus 2 organism-based format Scientific Literature 15. ALA4431073 T Toxicity in rabbit assessed as change in mean blood pressure at 3 mg/kg, iv as 30 mins infusion measured at 20 mins Oryctolagus cuniculus 2 organism-based format Scientific Literature 16. ALA4431074 T Toxicity in rabbit assessed as change in heart rate at 3 mg/kg, iv as 30 mins infusion measured at 20 mins Oryctolagus cuniculus 2 organism-based format Scientific Literature