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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4431051 B Inhibition of human Kv1.5 transfected in mouse LTK cells Homo sapiens 16 ALA4428127 cell-based format Scientific Literature 2. ALA4431052 B Inhibition of human Kv1.5 transfected in mouse LTK cells at 0.3 uM Homo sapiens 12 ALA4428127 cell-based format Scientific Literature 3. ALA4431053 B Inhibition of human ERG expressed in HEK293 cells by thallium flux assay Homo sapiens 16 ALA4428127 cell-based format Scientific Literature 4. ALA4431054 A Stability in rat liver microsomes Rattus norvegicus 1 ALA4428127 microsome format Scientific Literature 5. ALA4431055 A Clearance in Sprague-Dawley rat hemodynamic/VERP model at 2 mg/kg, iv Rattus norvegicus 2 ALA4428127 organism-based format Scientific Literature 6. ALA4431056 A Volume of distribution at steady state in Sprague-Dawley rat hemodynamic/VERP model at 2 mg/kg, iv Rattus norvegicus 2 ALA4428127 organism-based format Scientific Literature 7. ALA4431057 A Half life in Sprague-Dawley rat hemodynamic/VERP model at 2 mg/kg, iv Rattus norvegicus 2 ALA4428127 organism-based format Scientific Literature 8. ALA4431058 A Half life in Sprague-Dawley rat hemodynamic/VERP model at 5 mg/kg, po Rattus norvegicus 2 ALA4428127 organism-based format Scientific Literature 9. ALA4431059 A Oral bioavailability in Sprague-Dawley rat hemodynamic/VERP model at 5 mg/kg Rattus norvegicus 2 ALA4428127 organism-based format Scientific Literature 10. ALA4431060 A Pro-arrhythmic activity in rat assessed as plasma concentration required to increase 98 +/- 3% ventricular effective refractory period at 10 mg/kg, iv as 10 mins infusion Rattus norvegicus 1 ALA4428127 organism-based format Scientific Literature 11. ALA4431061 A Pro-arrhythmic activity in rat assessed as increase in ventricular effective refractory period at 10 mg/kg, iv as 10 mins infusion Rattus norvegicus 2 ALA4428127 organism-based format Scientific Literature 12. ALA4431062 F Increase in atrial effective refractory period in rabbit at 3 mg/kg, iv as 30 mins infusion measured at 20 mins Oryctolagus cuniculus 2 ALA4428127 organism-based format Scientific Literature 13. ALA4431063 A Plasma concentration in rabbit at 3 mg/kg, iv as 30 mins infusion Oryctolagus cuniculus 2 ALA4428127 organism-based format Scientific Literature 14. ALA4431072 T Toxicity in rabbit assessed as change in systolic blood pressure at 3 mg/kg, iv as 30 mins infusion measured at 20 mins Oryctolagus cuniculus 2 ALA4428127 organism-based format Scientific Literature 15. ALA4431073 T Toxicity in rabbit assessed as change in mean blood pressure at 3 mg/kg, iv as 30 mins infusion measured at 20 mins Oryctolagus cuniculus 2 ALA4428127 organism-based format Scientific Literature 16. ALA4431074 T Toxicity in rabbit assessed as change in heart rate at 3 mg/kg, iv as 30 mins infusion measured at 20 mins Oryctolagus cuniculus 2 ALA4428127 organism-based format Scientific Literature