# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4393554 | B | Inhibition of ovine COX1 assessed as reduction in prostaglandin E2 production at 30 uM incubated for 10 mins before arachidonic acid addition and measured after 25 mins by LC-MS/MS analysis | Ovis aries | 1 | ALA4392873 | single protein format | Scientific Literature | |
2. | ALA4393555 | B | Inhibition of COX2 (unknown origin) assessed as reduction in prostaglandin E2 production at 30 uM incubated for 10 mins before arachidonic acid addition and measured after 25 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA4392873 | single protein format | Scientific Literature | |
3. | ALA4393556 | B | Inhibition of ovine COX1 assessed as reduction in prostaglandin E2 production incubated for 10 mins before arachidonic acid addition and measured after 25 mins by LC-MS/MS analysis | Ovis aries | 1 | ALA4392873 | single protein format | Scientific Literature | |
4. | ALA4393557 | B | Inhibition of COX2 (unknown origin) assessed as reduction in prostaglandin E2 production incubated for 10 mins before arachidonic acid addition and measured after 25 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA4392873 | single protein format | Scientific Literature | |
5. | ALA4393558 | B | Selectivity index, ratio of IC50 for ovine COX1 to IC50 for COX2 (unknown origin) | 1 | ALA4392873 | assay format | Scientific Literature |