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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4372327 Binding Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using IGF-R1tide as substrate in presence of [gamma-33P]-ATP or [gamma-32P]-ATP Homo sapiens 18 ALA4371041 cell-based format Scientific Literature 2. ALA4372328 Binding Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells at 1 uM using IGF-R1tide as substrate in presence of [gamma-33P]-ATP or [gamma-32P]-ATP relative to control Homo sapiens 18 ALA4371041 cell-based format Scientific Literature 3. ALA4372329 Functional Growth inhibition of mouse NFS60 cells after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay Mus musculus 18 ALA4371041 cell-based format Scientific Literature 4. ALA4372330 ADME Half life in CD-1 mouse at 3 mg/kg, iv Mus musculus 2 ALA4371041 organism-based format Scientific Literature 5. ALA4372331 ADME Cmax in CD-1 mouse at 3 mg/kg, iv Mus musculus 2 ALA4371041 organism-based format Scientific Literature 6. ALA4372332 ADME AUC (0 to 7 hrs) in CD-1 mouse at 3 mg/kg, iv Mus musculus 2 ALA4371041 organism-based format Scientific Literature 7. ALA4372333 ADME Volume of distribution in CD-1 mouse at 3 mg/kg, iv Mus musculus 2 ALA4371041 organism-based format Scientific Literature 8. ALA4372334 ADME Clearance in CD-1 mouse at 3 mg/kg, iv Mus musculus 2 ALA4371041 organism-based format Scientific Literature 9. ALA4372335 ADME Half life in CD-1 mouse at 10 mg/kg, po Mus musculus 2 ALA4371041 organism-based format Scientific Literature 10. ALA4372336 ADME Cmax in CD-1 mouse at 10 mg/kg, po Mus musculus 2 ALA4371041 organism-based format Scientific Literature 11. ALA4372337 ADME Tmax in CD-1 mouse at 10 mg/kg, po Mus musculus 2 ALA4371041 organism-based format Scientific Literature 12. ALA4372338 ADME AUC (0 to 7 hrs) in CD-1 mouse at 10 mg/kg, po Mus musculus 2 ALA4371041 organism-based format Scientific Literature 13. ALA4372339 ADME Oral bioavailability in CD-1 mouse at 10 mg/kg Mus musculus 2 ALA4371041 organism-based format Scientific Literature 14. ALA4372340 ADME Stability in human hepatocytes assessed as parent compound remaining measured after 60 mins Homo sapiens 2 ALA4371041 cell-based format Scientific Literature 15. ALA4372341 ADME Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysis Homo sapiens 2 ALA4371041 microsome format Scientific Literature 16. ALA4372342 ADME Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysis Homo sapiens 2 ALA4371041 microsome format Scientific Literature 17. ALA4372343 ADME Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysis Homo sapiens 2 ALA4371041 microsome format Scientific Literature 18. ALA4372344 ADME Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysis Homo sapiens 2 ALA4371041 microsome format Scientific Literature 19. ALA4372345 ADME Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysis Homo sapiens 2 ALA4371041 microsome format Scientific Literature 20. ALA4372346 ADME Volume of distribution in CD-1 mouse at 10 mg/kg, po Mus musculus 1 ALA4371041 organism-based format Scientific Literature