| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4477701 | B | Inhibition of LPS-stimulated DNA binding activity of NF-kappaB p65 in mouse RAW264.7 cells assessed as at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 30 mins by ELISA method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4477702 | F | Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as reduction in nitrite production at 5 to 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs by Griess reaction | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4477703 | F | Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as reduction in PGE2 production at 5 to 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4477704 | F | Reduction in iNOS expression in LPS-stimulated mouse RAW264.7 cells at 5 to 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs by western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4477705 | F | Reduction in COX2 expression in LPS-stimulated mouse RAW264.7 cells at 5 to 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs by western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4477706 | F | Reduction in TNF-alpha production in LPS-stimulated mouse RAW264.7 cells at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4477707 | F | Reduction in IL-1beta production in LPS-stimulated mouse RAW264.7 cells at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4477708 | F | Reduction in IL6 production in LPS-stimulated mouse RAW264.7 cells at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4477709 | F | Reduction in TNF-alpha mRNA expression in LPS-stimulated mouse RAW264.7 cells at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs by real-time PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4477710 | F | Reduction in IL-1beta mRNA expression in LPS-stimulated mouse RAW264.7 cells at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs by real-time PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4477711 | F | Reduction in IL6 mRNA expression in LPS-stimulated mouse RAW264.7 cells at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs by real-time PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4477712 | B | Inhibition of LPS-stimulated NF-kappaB p50 nuclear translocation in mouse RAW264.7 cells at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 30 mins by western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4477713 | B | Inhibition of LPS-stimulated NF-kappaB p65 nuclear translocation in mouse RAW264.7 cells at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 30 mins by western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4477714 | B | Activation of Nrf2 in LPS-stimulated mouse RAW264.7 cells assessed as induction of HO-1 mRNA expression at 5 to 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 12 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4477715 | B | Increase in nuclear Nrf2 translocation in LPS-stimulated mouse RAW264.7 cells assessed as nuclear Nrf2 level at 20 and 40 uM measured up to 120 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4477716 | B | Increase in nuclear Nrf2 translocation in LPS-stimulated mouse RAW264.7 cells assessed as cytosolic Nrf2 level at 20 and 40 uM measured up to 120 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4477717 | F | Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as reduction in nitrite production at 5 to 40 uM pre-treated for 12 hrs prior to LPS-challenge measured after 18 hrs in presence of HO-1 competitive inhibitor SnPP by Griess reaction | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4477718 | F | Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as reduction in PGE2 production at 5 to 40 uM pre-treated for 12 hrs prior to LPS-challenge measured after 18 hrs in presence of HO-1 competitive inhibitor SnPP | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4477719 | F | Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as reduction in TNF-alpha production at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs iin presence of HO-1 competitive inhibitor SnPP | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4477720 | F | Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as reduction in IL-1beta production at 20 and 40 uM pre-treated for 6 hrs prior to LPS-challenge measured after 24 hrs in presence of competitive inhibitor of HO-1 SnPP | Mus musculus | 1 | cell-based format | Scientific Literature |
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