| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4478651 | ADME | Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate after 10 mins by LC/MS/MS analysis | Homo sapiens | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 2. | ALA4478652 | ADME | Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 10 mins by LC/MS/MS analysis | Homo sapiens | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 3. | ALA4478656 | Binding | Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAEG as substrate preincubated for 20 mins followed by substrate addition measured after 30 mins by Alphascreen assay | Homo sapiens | 21 | ALA4477217 | cell-based format | Scientific Literature | |
| 4. | ALA4478657 | Binding | Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAEG as substrate preincubated for 20 mins followed by substrate addition measured after 30 mins by Alphascreen assay | Homo sapiens | 21 | ALA4477217 | cell-based format | Scientific Literature | |
| 5. | ALA4478658 | Binding | Inhibition of full length unphosphorylated AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAEG as substrate preincubated for 20 mins followed by substrate addition measured after 30 mins by Alphascreen assay | Homo sapiens | 21 | ALA4477217 | cell-based format | Scientific Literature | |
| 6. | ALA4478659 | Functional | Antiproliferative activity against human A2780 cells after 72 hrs by MTS/PMS assay | Homo sapiens | 5 | ALA4477217 | cell-based format | Scientific Literature | |
| 7. | ALA4478660 | Functional | Antiproliferative activity against human AN3CA cells after 72 hrs by MTS/PMS assay | Homo sapiens | 5 | ALA4477217 | cell-based format | Scientific Literature | |
| 8. | ALA4478661 | Functional | Antiproliferative activity against human IGROV1 cells after 72 hrs by MTS/PMS assay | Homo sapiens | 5 | ALA4477217 | cell-based format | Scientific Literature | |
| 9. | ALA4478662 | Functional | Antiproliferative activity against human LNCAP cells after 72 hrs by MTS/PMS assay | Homo sapiens | 5 | ALA4477217 | cell-based format | Scientific Literature | |
| 10. | ALA4478669 | ADME | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 10 mins by LC/MS/MS analysis | Homo sapiens | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 11. | ALA4478670 | ADME | Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate after 10 mins by LC/MS/MS analysis | Homo sapiens | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 12. | ALA4478671 | ADME | Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC/MS/MS analysis | Homo sapiens | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 13. | ALA4478672 | ADME | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysis | Homo sapiens | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 14. | ALA4478673 | ADME | Half life in human liver microsomes at 1 uM in presence of NADPH by LC/MS/MS analysis | Homo sapiens | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 15. | ALA4478674 | ADME | Half life in female CD-1 mouse liver microsomes at 1 uM in presence of NADPH by LC/MS/MS analysis | Mus musculus | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 16. | ALA4478675 | ADME | Half life in male CD-1 mouse liver microsomes at 1 uM in presence of NADPH by LC/MS/MS analysis | Mus musculus | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 17. | ALA4478676 | ADME | Half life in female Beagle dog liver microsomes at 1 uM in presence of NADPH by LC/MS/MS analysis | Canis lupus familiaris | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 18. | ALA4478677 | ADME | Half life in male Beagle dog liver microsomes at 1 uM in presence of NADPH by LC/MS/MS analysis | Canis lupus familiaris | 6 | ALA4477217 | microsome format | Scientific Literature | |
| 19. | ALA4478678 | Physicochemical | Solubility of the compound | 6 | ALA4477217 | small-molecule physicochemical format | Scientific Literature |
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