# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4430888 | F | Antioxidant activity in FRDA patient derived lymphocyte GM15850 assessed as inhibition of DEM-induced lipid peroxidation at 0.1 to 1 uM pre-incubated for 16 hrs followed by DEM addition for 120 mins by C11-BODIPY581/591 probe based flow cytometry relative to control | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
2. | ALA4430890 | F | Antioxidant activity in FRDA patient derived lymphocyte GM15850 assessed as suppression of DEM-induced intracellular ROS levels at 100 nM pre-incubated for 16 hrs followed by DEM addition for 80 mins by DCFH-DA probe based flow cytometry | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
3. | ALA4430892 | F | Inhibition of DEM-induced collapse of mitochondrial membrane potential in FRDA patient derived lymphocyte GM15850 assessed as intact mitochondrial membrane potential at 100 nM pre-incubated for 16 hrs followed by DEM addition for 120 mins by TMRM dye based flow cytometry (Rvb = 91.3 %) | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
4. | ALA4430893 | F | Inhibition of DEM-induced collapse of mitochondrial membrane potential in FRDA patient derived lymphocyte GM15850 assessed as intact mitochondrial membrane potential at 1000 nM pre-incubated for 16 hrs followed by DEM addition for 120 mins by TMRM dye based flow cytometry (Rvb = 91.3 %) | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
5. | ALA4430894 | F | Inhibition of DEM-induced collapse of mitochondrial membrane potential in FRDA patient derived lymphocyte GM15850 assessed as intact mitochondrial membrane potential at 2500 nM pre-incubated for 16 hrs followed by DEM addition for 120 mins by TMRM dye based flow cytometry (Rvb = 91.3 %) | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
6. | ALA4430895 | F | Inhibition of DEM-induced collapse of mitochondrial membrane potential in FRDA patient derived lymphocyte GM15850 assessed as intact mitochondrial membrane potential pre-incubated for 16 hrs followed by DEM addition for 120 mins by TMRM dye based flow cytometry | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
7. | ALA4430896 | A | Effect on mitochondrial membrane potential in FRDA patient derived lymphocyte GM15850 incubated for 16 hrs by TMRM dye based flow cytometry | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
8. | ALA4430897 | F | Increase in total intracellular ATP levels in FRDA patient derived lymphocyte GM15850 grown in galactose medium at 1 uM after 48 hrs by luciferin-luciferase reaction based bioluminescence assay relative to control | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
9. | ALA4430898 | F | Increase in total intracellular ATP levels in FRDA patient derived lymphocyte GM15850 grown in galactose medium at 5 uM after 48 hrs by luciferin-luciferase reaction based bioluminescence assay relative to control | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
10. | ALA4430899 | F | Increase in total intracellular ATP levels in FRDA patient derived lymphocyte GM15850 grown in galactose medium at 20 uM after 48 hrs by luciferin-luciferase reaction based bioluminescence assay relative to control | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
11. | ALA4430901 | F | Cytoprotective activity against DEM induced oxidative stress in FRDA patient derived lymphocyte GM15850 assessed as cell viability at 0.5 uM pre-incubated for 16 hrs followed by DEM addition for 6 hrs by calcein AM/EthD-1 staining based flow cytometry | Homo sapiens | 8 | ALA4428118 | cell-based format | Scientific Literature | |
12. | ALA4430902 | F | Cytoprotective activity against DEM induced oxidative stress in FRDA patient derived lymphocyte GM15850 assessed as cell viability at 0.1 uM pre-incubated for 16 hrs followed by DEM addition for 6 hrs by calcein AM/EthD-1 staining based flow cytometry | Homo sapiens | 9 | ALA4428118 | cell-based format | Scientific Literature | |
13. | ALA4430903 | A | Stability in bovine liver microsomes assessed as drug recovery at 25 uM after 30 mins in presence of beta-NADPH by HPLC analysis | Bos taurus | 9 | ALA4428118 | microsome format | Scientific Literature |
per page
Shop By
Filters
Type Label
Classifications L1
Classifications L2
Classifications L3
Organism Taxonomy L1
Organism Taxonomy L2
Organism Taxonomy L3
Organism
BAO Format
Source
Compare Products
You have no items to compare.
My Wish List
Last Added Items
You have no items in your wish list.