#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4352637	ADME	Inhibition of N-terminal His6-tagged recombinant full length human p110beta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate measured after 80 mins by transcreener fluorescence polarization assay	Homo sapiens	16	ALA4350965	cell-based format	Scientific Literature
2.	ALA4352638	Binding	Inhibition of recombinant human full-length His-tagged PI3K p110gamma expressed in baculovirus expression system using PIP2 as substrate measured after 80 mins by transcreener fluorescence polarization assay	Homo sapiens	23	ALA4350965	assay format	Scientific Literature
3.	ALA4352639	Binding	Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate measured after 80 mins by transcreener fluorescence polarization assay	Homo sapiens	23	ALA4350965	cell-based format	Scientific Literature
4.	ALA4352651	Binding	Inhibition of PI3Kdelta in human whole blood assessed as reduction in anti-IgM-stimulated CD69 expression on B-cells preincubated for 60 mins followed by anti-IgM stimulation and measured after overnight incubation by flow cytometry	Homo sapiens	2	ALA4350965	tissue-based format	Scientific Literature
5.	ALA4352652	Binding	Inhibition of PI3Kdelta in rat whole blood assessed as reduction in anti-IgD-stimulated CD86 expression on B-cells preincubated for 60 mins followed by anti-IgD stimulation and measured after overnight incubation by flow cytometry	Rattus norvegicus	2	ALA4350965	tissue-based format	Scientific Literature
6.	ALA4352654	Binding	Inhibition of PI3Kgamma in human whole blood assessed as reduction in anti-IgE-stimulated CD63 expression in basophils preincubated for 30 mins followed by anti-IgE stimulation	Homo sapiens	2	ALA4350965	tissue-based format	Scientific Literature
7.	ALA4352655	Binding	Inhibition of PI3Kdelta in human whole blood assessed as reduction in fMLP-stimulated CD63 expression in basophils preincubated for 30 mins followed by fMLP stimulation	Homo sapiens	2	ALA4350965	tissue-based format	Scientific Literature
8.	ALA4352656	Functional	Ex vivo inhibition of anti-IgD-induced B cell activation in Wistar rat assessed as CD86 expression at 1 mg/kg, po pretreated for 2 hrs followed by anti-IgD stimulation and measured after overnight incubation by flow cytometry relative to control	Rattus norvegicus	1	ALA4350965	organism-based format	Scientific Literature
9.	ALA4352657	Functional	Antiarthritic activity in po dosed type2 collagen-induced Wistar rat arthritis model assessed as reduction in hind paw volume administered twice daily for 7 days and measured daily during compound dosing by plethysmometry	Rattus norvegicus	1	ALA4350965	organism-based format	Scientific Literature
10.	ALA4352658	ADME	Glutathione reactivity in human liver microsomes assessed as GSH-adduct formation at 1 uM measured after 30 mins in presence of NADPH generating system	Homo sapiens	1	ALA4350965	microsome format	Scientific Literature
11.	ALA4352659	ADME	AUC in Beagle dog at 1 mg/kg, iv by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4350965	organism-based format	Scientific Literature
12.	ALA4352660	ADME	Volume of distribution at steady state in Beagle dog at 1 mg/kg, iv by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4350965	organism-based format	Scientific Literature
13.	ALA4352661	ADME	Half life in Beagle dog at 1 mg/kg, iv by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4350965	organism-based format	Scientific Literature
14.	ALA4352662	ADME	Clearance in Beagle dog at 1 mg/kg, iv by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4350965	organism-based format	Scientific Literature
15.	ALA4352663	Functional	Inhibition of KC/GRO-induced neutrophil migration in Wistar rat air pouch model at 10 mg/kg, po pretreated for 0.5 hrs followed by KC/GRO-stimulation and measured after 4 hrs by flow cytometry relative to control	Rattus norvegicus	1	ALA4350965	organism-based format	Scientific Literature
16.	ALA4352664	ADME	Cmax in Beagle dog at 5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4350965	organism-based format	Scientific Literature
17.	ALA4352665	ADME	AUC in Beagle dog at 5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4350965	organism-based format	Scientific Literature
18.	ALA4352666	ADME	Oral bioavailability in Sprague-Dawley rat at 10 mg/kg by LC-MS/MS analysis	Rattus norvegicus	1	ALA4350965	organism-based format	Scientific Literature
19.	ALA4352667	ADME	Cmax in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS analysis	Rattus norvegicus	1	ALA4350965	organism-based format	Scientific Literature
20.	ALA4352668	ADME	AUC in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS analysis	Rattus norvegicus	1	ALA4350965	organism-based format	Scientific Literature