| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4325427 | Binding | Inhibition of p300 (unknown origin) using histone H3 (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate and [3H]acetyl-CoA addition and measured after 60 mins by scintillation counting analysis | Homo sapiens | 28 | ALA4321876 | single protein format | Scientific Literature | |
| 2. | ALA4325428 | Functional | Antiproliferative activity against human MV4-11 cells measured after 3 days by celltiter-glo luminescence assay | Homo sapiens | 28 | ALA4321876 | cell-based format | Scientific Literature | |
| 3. | ALA4325429 | ADME | Intrinsic clearance in human liver microsomes assessed per mg protein at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured up to 60 mins by UPLC-MS/MS analysis | Homo sapiens | 28 | ALA4321876 | microsome format | Scientific Literature | |
| 4. | ALA4325430 | ADME | Intrinsic clearance in rat liver microsomes assessed per mg protein at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured up to 60 mins by UPLC-MS/MS analysis | Rattus norvegicus | 28 | ALA4321876 | microsome format | Scientific Literature | |
| 5. | ALA4325431 | ADME | Intrinsic clearance in mouse liver microsomes assessed per mg protein at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured up to 60 mins by UPLC-MS/MS analysis | Mus musculus | 28 | ALA4321876 | microsome format | Scientific Literature |
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