# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4390455 | ADME | Stability in human liver microsomes assessed as parent compound remaining after 10 mins | Homo sapiens | 35 | ALA4387773 | microsome format | Scientific Literature | |
2. | ALA4390456 | Binding | Inverse agonist activity at human Gal4-fused RORgammat LBD (267 to 516 residues) expressed in human Jurkat cells measured after 18 hrs by steady-glo luciferase reporter gene assay | Homo sapiens | 34 | ALA4387773 | cell-based format | Scientific Literature | |
3. | ALA4390457 | Binding | Transactivation of PXR (unknown origin) expressed in human HepG2 cells | Homo sapiens | 34 | ALA4387773 | cell-based format | Scientific Literature | |
4. | ALA4390458 | Binding | Transactivation of PXR (unknown origin) expressed in human HepG2 cells assessed as maximum receptor activation response relative to control | Homo sapiens | 34 | ALA4387773 | cell-based format | Scientific Literature | |
5. | ALA4390459 | ADME | Stability in mouse liver microsomes assessed as parent compound remaining after 10 mins | Mus musculus | 35 | ALA4387773 | microsome format | Scientific Literature | |
6. | ALA4390460 | Binding | Inverse agonist activity at human Gal4-fused RORalpha LBD (272 to 556 residues) expressed in human Jurkat cells measured after 18 hrs by steady-glo luciferase reporter gene assay | Homo sapiens | 35 | ALA4387773 | cell-based format | Scientific Literature | |
7. | ALA4390461 | Binding | Inverse agonist activity at human Gal4-fused RORbeta LBD (200 to 559 residues) expressed in human Jurkat cells measured after 18 hrs by steady-glo luciferase reporter gene assay | Homo sapiens | 35 | ALA4387773 | cell-based format | Scientific Literature | |
8. | ALA4390462 | Binding | Transactivation of human GAL4-fused LXRalpha expressed in African green monkey CV1 cells | Homo sapiens | 35 | ALA4387773 | cell-based format | Scientific Literature | |
9. | ALA4390463 | Binding | Transactivation of human GAL4-fused LXRbeta expressed in African green monkey CV1 cells | Homo sapiens | 35 | ALA4387773 | cell-based format | Scientific Literature |