# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4353029 | Functional | Antitrypanosomal activity against Trypanosoma cruzi strain Y trypomastigotes maintained in Rhesus monkey LLC-MK1 cells assessed as decrease in trypomastigotes cell viability incubated for 24 hrs by resazurin dye based colorimetric assay | Trypanosoma cruzi | 26 | ALA4350979 | organism-based format | Scientific Literature | |
2. | ALA4353031 | Functional | Antitrypanosomal activity against Trypanosoma cruzi amastigotes infected in BALB/c mouse peritoneal macrophages assessed as decrease in parasitic load with in the cell incubated for 48 hrs by Giemsa staining based light microscopy | Trypanosoma cruzi | 26 | ALA4350979 | organism-based format | Scientific Literature | |
3. | ALA4353032 | ADME | Cytotoxicity against mouse NCTC-929 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Mus musculus | 26 | ALA4350979 | cell-based format | Scientific Literature | |
4. | ALA4726502 | Functional | Cytotoxicity against mouse B16-F10 cells | Mus musculus | 29 | ALA4725273 | cell-based format | Scientific Literature | |
5. | ALA4726503 | Functional | Cytotoxicity against human A2058 cells | Homo sapiens | 30 | ALA4725273 | cell-based format | Scientific Literature | |
6. | ALA4726504 | ADME | Cytotoxicity against human T75 cells | Homo sapiens | 30 | ALA4725273 | cell-based format | Scientific Literature | |
7. | ALA4726505 | Unassigned | Selectivity index, ratio for IC50 for human T75 cells to IC50 for human A2058 cells | Homo sapiens | 16 | ALA4725273 | assay format | Scientific Literature |