| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4411721 | B | Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha after 6 hrs by luciferase reporter gene assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 2. | ALA4411722 | B | Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha after 6 hrs by luciferase reporter gene assay relative to deferoxamine | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 3. | ALA4411723 | B | Inhibition of PHD in HEK293T cells assessed as increase in HIF1alpha expression at 1 to 10 uM after 3 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4411724 | A | Effect on PHD2 expression in HEK293T cells at 1 to 10 uM after 3 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4411725 | A | Effect on PHD1 expression in HEK293T cells at 1 to 10 uM after 3 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4411726 | A | Effect on PHD3 expression in HEK293T cells at 1 to 10 uM after 3 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4411727 | B | Inhibition of PHD in HEK293T cells assessed as increase in HIF1alpha expression at 10 uM after 15 to 180 mins by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4411728 | B | Inhibition of PHD in HEK293T cells assessed as increase in HIF1alpha expression at 10 uM under hypoxic condition by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4411729 | A | Effect on PHD2 expression in HEK293T cells at 10 uM under hypoxic condition by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4411730 | A | Effect on PHD2 expression in HEK293T cells at 10 uM under normoxic condition by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4411731 | B | Inhibition of PHD in HEK293T cells assessed as increase in HIF1alpha expression at 10 uM under normoxic condition by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4411732 | B | Inhibition of PHD in HEK293T cells assessed as increase in HIF1alpha expression at 1 to 10 uM after 6 hrs in presence of proteasome inhibitor MG132 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4411733 | B | Inhibition of PHD in HEK293T cells assessed as reduction in HIF1alpha hydroxylation at 1 to 10 uM after 6 hrs in presence of proteasome inhibitor MG132 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4411734 | B | Reversible inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha at 5 to 25 uM pretreated for 1 hr followed by compound washout and measured after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4411735 | B | Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha at 1 to 25 uM after 6 hrs in presence of 50 uM betulinic acid by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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