# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4311439 | ADME | Cytotoxicity against human BJ cells after 48 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 12 | ALA4308899 | cell-based format | Scientific Literature | |
2. | ALA4311440 | Functional | Antiproliferative activity against human PC3 cells after 48 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 12 | ALA4308899 | cell-based format | Scientific Literature | |
3. | ALA4311441 | Functional | Antiproliferative activity against human HF6 cells after 48 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 12 | ALA4308899 | cell-based format | Scientific Literature | |
4. | ALA4311442 | Functional | Antiproliferative activity against human CaSki cells after 48 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 12 | ALA4308899 | cell-based format | Scientific Literature | |
5. | ALA4311443 | Functional | Antiproliferative activity against human MCF7 cells after 48 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 12 | ALA4308899 | cell-based format | Scientific Literature | |
6. | ALA4311453 | Functional | Cell cycle arrest in human PC3 cells assessed as accumulation at sub-G1 phase at 8.2 uM after 48 hrs by RNAse/propidium iodide staining-based flow cytometric analysis (Rvb = 0.00%) | Homo sapiens | 1 | ALA4308899 | cell-based format | Scientific Literature | |
7. | ALA4311454 | Functional | Cell cycle arrest in human PC3 cells assessed as accumulation at G1 phase at 8.2 uM after 48 hrs by RNAse/propidium iodide staining-based flow cytometric analysis (Rvb = 55.6%) | Homo sapiens | 1 | ALA4308899 | cell-based format | Scientific Literature | |
8. | ALA4311455 | Functional | Cell cycle arrest in human PC3 cells assessed as accumulation at S phase at 8.2 uM after 48 hrs by RNAse/propidium iodide staining-based flow cytometric analysis (Rvb = 19.7%) | Homo sapiens | 1 | ALA4308899 | cell-based format | Scientific Literature | |
9. | ALA4311456 | Functional | Cell cycle arrest in human PC3 cells assessed as accumulation at G2/M phase at 8.2 uM after 48 hrs by RNAse/propidium iodide staining-based flow cytometric analysis (Rvb = 24.9%) | Homo sapiens | 1 | ALA4308899 | cell-based format | Scientific Literature | |
10. | ALA4311461 | Functional | Induction of apoptosis in human PC3 cells assessed as chromatin condensation at IC50 after 48 hrs by acridine orange/ethidium bromide staining-based epifluorescence microscopic analysis | Homo sapiens | 3 | ALA4308899 | cell-based format | Scientific Literature | |
11. | ALA4311462 | Functional | Induction of apoptosis in human PC3 cells assessed as plasma membrane blebbing at IC50 after 48 hrs by acridine orange/ethidium bromide staining-based epifluorescence microscopic analysis | Homo sapiens | 3 | ALA4308899 | cell-based format | Scientific Literature | |
12. | ALA4311463 | Functional | Induction of apoptosis in human PC3 cells assessed as formation of apoptotic bodies at IC50 after 48 hrs by acridine orange/ethidium bromide staining-based epifluorescence microscopic analysis | Homo sapiens | 3 | ALA4308899 | cell-based format | Scientific Literature | |
13. | ALA4311470 | Functional | Induction of apoptosis in human PC3 cells assessed as down regulation of Bcl2 mRNA expression after 48 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA4308899 | cell-based format | Scientific Literature | |
14. | ALA4311471 | Functional | Induction of apoptosis in human PC3 cells assessed as upregulation of Bax mRNA expression after 48 hrs by RT-PCR analysis | Homo sapiens | 3 | ALA4308899 | cell-based format | Scientific Literature | |
15. | ALA4311472 | Functional | Induction of apoptosis in human PC3 cells assessed as increase in caspase 3/7 activity by Caspase 3/7-Glo luminescence assay | Homo sapiens | 3 | ALA4308899 | cell-based format | Scientific Literature | |
16. | ALA4403436 | Functional | Cytotoxicity against human PC3 cells assessed as reduction in cell viability | Homo sapiens | 5 | ALA4402531 | cell-based format | Scientific Literature |