# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4354500 | Functional | Antioxidant activity assessed as ABTS radical scavenging activity at 1 mg/ml by spectrophotometric analysis relative to ascorbic acid | 18 | ALA4351019 | assay format | Scientific Literature | ||
2. | ALA4354501 | Functional | Antioxidant activity assessed as DPPH radical scavenging activity at 1 uM measured after 30 mins by spectrophotometric analysis relative to ascorbic acid | 18 | ALA4351019 | assay format | Scientific Literature | ||
3. | ALA4354503 | Functional | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 19 | ALA4351019 | cell-based format | Scientific Literature | |
4. | ALA4354504 | Functional | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 19 | ALA4351019 | cell-based format | Scientific Literature | |
5. | ALA4354505 | ADME | Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 19 | ALA4351019 | cell-based format | Scientific Literature | |
6. | ALA4354506 | Toxicity | Selectivity index, ratio of IC50 for human WI38 cells to IC50 for HepG2 cells | Homo sapiens | 18 | ALA4351019 | assay format | Scientific Literature | |
7. | ALA4354507 | Toxicity | Selectivity index, ratio of IC50 for human WI38 cells to IC50 for human MCF7 cells | Homo sapiens | 19 | ALA4351019 | assay format | Scientific Literature | |
8. | ALA4354508 | Functional | Induction of apoptosis in human HepG2 cells assessed as down regulation of Bcl2 expression at cytotoxicity IC50 incubated for 48 hrs by ELISA | Homo sapiens | 3 | ALA4351019 | cell-based format | Scientific Literature | |
9. | ALA4354510 | Functional | Induction of apoptosis in human HepG2 cells assessed as up regulation of IL-2 expression at cytotoxicity IC50 incubated for 48 hrs by ELISA | Homo sapiens | 3 | ALA4351019 | cell-based format | Scientific Literature | |
10. | ALA4354513 | Functional | Induction of apoptosis in human HepG2 cells assessed as up regulation of IL-6 expression at cytotoxicity IC50 incubated for 48 hrs by ELISA relative to control | Homo sapiens | 3 | ALA4351019 | cell-based format | Scientific Literature | |
11. | ALA4354514 | Functional | Induction of apoptosis in human HepG2 cells assessed as up regulation of CD40 expression at cytotoxicity IC50 incubated for 48 hrs by ELISA | Homo sapiens | 2 | ALA4351019 | cell-based format | Scientific Literature | |
12. | ALA4354516 | Functional | Antioxidant activity assessed as DPPH radical scavenging activity at 1 uM measured after 30 mins by spectrophotometric analysis relative to control | 19 | ALA4351019 | assay format | Scientific Literature | ||
13. | ALA4354517 | Functional | Antioxidant activity assessed as ABTS radical scavenging activity at 1 mg/ml by spectrophotometric analysis relative to control | 19 | ALA4351019 | assay format | Scientific Literature | ||
14. | ALA4354518 | Unassigned | Prooxidant activity in calf thymus DNA assessed as increase in bleomycin-induced DNA damage by measuring optical density at 2 mM incubated for 1 hr by spectrophotometry relative to control | 17 | ALA4351019 | assay format | Scientific Literature | ||
15. | ALA4354519 | Unassigned | GPx-like activity of the compound assessed as oxidation of NADPH to NADP+ by measuring optical density at 41 uM measured for 3 mins by spectrophotometry | 16 | ALA4351019 | assay format | Scientific Literature |