| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4368282 | Binding | Inhibition of recombinant His-tagged FGFR4 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as covalent modification measured after < 3 secs by LC-MS/MS analysis | Homo sapiens | 5 | ALA4364330 | assay format | Scientific Literature | |
| 2. | ALA4368283 | ADME | Inhibition of recombinant His-tagged FGFR3 C582S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) measured after 2 hrs by LC-MS/MS analysis relative to control | Homo sapiens | 5 | ALA4364330 | assay format | Scientific Literature | |
| 3. | ALA4368284 | ADME | Inhibition of recombinant His-tagged FGFR1 C584S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) measured after 2 hrs by LC-MS/MS analysis relative to control | Homo sapiens | 5 | ALA4364330 | assay format | Scientific Literature | |
| 4. | ALA4368285 | Binding | Inhibition of recombinant His-tagged FGFR2 (unknown origin) expressed in Escherichia coli BL21 (DE3) measured after 2 hrs by LC-MS/MS analysis relative to control | Homo sapiens | 5 | ALA4364330 | assay format | Scientific Literature | |
| 5. | ALA4833167 | ADME | Inhibition of FGFR1 (unknown origin) | Homo sapiens | 6 | ALA4831525 | single protein format | Scientific Literature | |
| 6. | ALA4833169 | ADME | Inhibition of FGFR2 (unknown origin) | Homo sapiens | 7 | ALA4831525 | single protein format | Scientific Literature | |
| 7. | ALA4833171 | ADME | Inhibition of FGFR3 (unknown origin) | Homo sapiens | 7 | ALA4831525 | single protein format | Scientific Literature | |
| 8. | ALA4833201 | Binding | Inhibition of FGFR4 (unknown origin) | Homo sapiens | 2 | ALA4831525 | single protein format | Scientific Literature | |
| 9. | ALA5168100 | Binding | Selectivity ratio of IC50 for FGFR1 (unknown origin) to IC50 for human C-terminal histidine tagged FGFR4 (450 to 751 residues) expressed in Sf21 insect cells | Homo sapiens | 1 | ALA5154932 | cell-based format | Scientific Literature | |
| 10. | ALA5168101 | Functional | Antiproliferative activity against human SNU-16 cells expressing FGFR2 assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 3 | ALA5154932 | cell-based format | Scientific Literature | |
| 11. | ALA5168102 | Functional | Antiproliferative activity against human RT-112 cells expressing FGFR3 assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 3 | ALA5154932 | cell-based format | Scientific Literature | |
| 12. | ALA5168103 | Binding | Inhibition of wild type FGFR1 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA | Homo sapiens | 36 | ALA5154932 | single protein format | Scientific Literature | |
| 13. | ALA5168104 | Binding | Inhibition of FGFR4 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA | Homo sapiens | 36 | ALA5154932 | single protein format | Scientific Literature | |
| 14. | ALA5168105 | Functional | Antiproliferative activity against human Hep3B cells expressing FGF19/FGFR4 assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 31 | ALA5154932 | cell-based format | Scientific Literature | |
| 15. | ALA5168106 | Functional | Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 30 | ALA5154932 | cell-based format | Scientific Literature | |
| 16. | ALA5168107 | Binding | Selectivity ratio of IC50 for FGFR1 (unknown origin) to IC50 for FGFR4 (unknown origin) | Homo sapiens | 30 | ALA5154932 | assay format | Scientific Literature | |
| 17. | ALA5168108 | Binding | Inhibition of wild type FGFR2 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA | Homo sapiens | 2 | ALA5154932 | single protein format | Scientific Literature | |
| 18. | ALA5168109 | Binding | Inhibition of wild type FGFR3 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA | Homo sapiens | 2 | ALA5154932 | single protein format | Scientific Literature | |
| 19. | ALA5168110 | Binding | Inhibition of FGFR4 V550L mutant (unknown origin) at 1 uM using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA | Homo sapiens | 2 | ALA5154932 | single protein format | Scientific Literature | |
| 20. | ALA5168111 | Functional | Antiproliferative activity against human NCI-H1581 cells expressing FGFR1 assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 3 | ALA5154932 | cell-based format | Scientific Literature |
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