# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4364915 | Functional | Antiproliferative activity against AR-positive human LNCAP cells assessed as cell viability at 40 uM measured after 72 hrs by resazurin dye based fluorescence assay relative to control | Homo sapiens | 8 | ALA4364252 | cell-based format | Scientific Literature | |
2. | ALA4364916 | Functional | Antiproliferative activity against AR-positive human LAPC4 cells assessed as cell viability at 40 uM measured after 72 hrs by resazurin dye based fluorescence assay relative to control | Homo sapiens | 8 | ALA4364252 | cell-based format | Scientific Literature | |
3. | ALA4364917 | Functional | Antiproliferative activity against AR-negative human PC3 cells assessed as cell viability at 40 uM measured after 72 hrs by resazurin dye based fluorescence assay relative to control | Homo sapiens | 13 | ALA4364252 | cell-based format | Scientific Literature | |
4. | ALA4364918 | Functional | Antiproliferative activity against AR-positive human 22Rv1 cells harboring ARE14 construct assessed as cell viability at 40 uM measured after 72 hrs by resazurin dye based fluorescence assay relative to control | Homo sapiens | 13 | ALA4364252 | cell-based format | Scientific Literature | |
5. | ALA4364919 | Functional | Antiproliferative activity against AR-positive human VCaP cells assessed as cell viability at 40 uM measured after 72 hrs by resazurin dye based fluorescence assay relative to control | Homo sapiens | 13 | ALA4364252 | cell-based format | Scientific Literature | |
6. | ALA4364925 | Functional | Effect on AR-V7 variant protein expression in AR-positive human 22Rv1 cells harboring ARE14 construct at 10 uM after 24 hrs by immunoblot analysis | Homo sapiens | 12 | ALA4364252 | cell-based format | Scientific Literature | |
7. | ALA4364926 | Binding | Inhibition of AR transcriptional activity in AR-positive human 22Rv1 cells harboring ARE14 construct assessed as suppression of NKX3.1 expression at 10 uM after 24 hrs by immunoblot analysis | Homo sapiens | 10 | ALA4364252 | assay format | Scientific Literature | |
8. | ALA4364927 | Binding | Inhibition of AR transcriptional activity in AR-positive human 22Rv1 cells harboring ARE14 construct assessed as suppression of PSA expression at 10 uM after 24 hrs by immunoblot analysis | Homo sapiens | 13 | ALA4364252 | assay format | Scientific Literature | |
9. | ALA4364939 | Functional | Antiproliferative activity against AR-positive human LAPC4 cells assessed as growth inhibition measured after 72 hrs by resazurin dye based fluorescence assay | Homo sapiens | 7 | ALA4364252 | cell-based format | Scientific Literature | |
10. | ALA4364940 | Functional | Antiproliferative activity against AR-positive human LNCAP cells assessed as growth inhibition measured after 72 hrs by resazurin dye based fluorescence assay | Homo sapiens | 7 | ALA4364252 | cell-based format | Scientific Literature | |
11. | ALA4364941 | Functional | Antiproliferative activity against AR-negative human PC3 cells assessed as growth inhibition measured after 72 hrs by resazurin dye based fluorescence assay | Homo sapiens | 12 | ALA4364252 | cell-based format | Scientific Literature | |
12. | ALA4364942 | Functional | Antiproliferative activity against human AR-positive 22Rv1 cells harboring ARE14 construct assessed as growth inhibition measured after 72 hrs by resazurin dye based fluorescence assay | Homo sapiens | 12 | ALA4364252 | cell-based format | Scientific Literature | |
13. | ALA4364943 | Functional | Antiproliferative activity against AR-positive human VCaP cells assessed as growth inhibition measured after 72 hrs by resazurin dye based fluorescence assay | Homo sapiens | 12 | ALA4364252 | cell-based format | Scientific Literature | |
14. | ALA4364944 | Binding | Inhibition of R1881 induced-AR transcriptional activity in AR-positive human 22Rv1 cells harboring ARE14 construct at 10 uM after 24 hrs by luciferase assay | Homo sapiens | 13 | ALA4364252 | assay format | Scientific Literature |