# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4383567 | Functional | Antitumor activity against human ECA109 cells xenografted in BALB/c nude mouse assessed as tumor size at 5 mg/kg, iv treated for 24 hrs before 120 J/cm2 laser light irradiation for 5 mins and measured every other day up to 14 days (Rvb = 785 +/- 37 mm3) | Homo sapiens | 1 | ALA4382209 | organism-based format | Scientific Literature | |
2. | ALA4383569 | Functional | Induction of singlet oxygen generation assessed as singlet oxygen quantum yield by measuring DPBF chemical oxidation in DMF solution incubated up to 5 mins at 5 mW/cm2 laser irradiation by UV-Vis spectrophotometry | 2 | ALA4382209 | assay format | Scientific Literature | ||
3. | ALA4383571 | Toxicity | Dark toxicity in human ECA109 cells assessed as decrease in cell viability after 24 hrs by MTT assay | Homo sapiens | 12 | ALA4382209 | cell-based format | Scientific Literature | |
4. | ALA4383572 | Functional | Phototoxicity against human ECA109 cells assessed as decrease in cell viability after 24 hrs at 16 J/cm2 irradiation by MTT assay | Homo sapiens | 12 | ALA4382209 | cell-based format | Scientific Literature | |
5. | ALA4383573 | Toxicity | Dark toxicity in human ECA109 cells assessed as cell survival at 20 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 12 | ALA4382209 | cell-based format | Scientific Literature | |
6. | ALA4383574 | ADME | Drug uptake in mitochondria of human ECA109 cells at 10 uM after 4 hrs by by Mito Tracker green dye-based confocal fluorescence microscopic method | Homo sapiens | 1 | ALA4382209 | mitochondrion format | Scientific Literature | |
7. | ALA4383575 | ADME | Drug uptake in lysosomes of human ECA109 cells at 10 uM after 4 hrs by Lyso Blue dye-based confocal fluorescence microscopic method | Homo sapiens | 1 | ALA4382209 | subcellular format | Scientific Literature | |
8. | ALA4383576 | Functional | Antitumor activity against human ECA109 cells xenografted in BALB/c nude mouse assessed as tumor size at 5 mg/kg, iv measured every other day up to 14 days | Homo sapiens | 1 | ALA4382209 | organism-based format | Scientific Literature |