# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4410579 | B | Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth after 96 hrs by Cell-Titer Blue assay | Homo sapiens | 6 | ALA4406895 | cell-based format | Scientific Literature | |
2. | ALA4410580 | A | Antiproliferative activity in Chinese hamster R2 cells deficient in RFC, PCFT, and FRalpha assessed as reduction in cell growth after 96 hrs by Cell-Titer Blue assay | Cricetulus griseus | 6 | ALA4406895 | cell-based format | Scientific Literature | |
3. | ALA4410581 | B | Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth after 96 hrs by Cell-Titer Blue assay | Homo sapiens | 6 | ALA4406895 | cell-based format | Scientific Literature | |
4. | ALA4410582 | B | Binding affinity to human PCFT expressed in Chinese hamster R2/PCFT4 cells assessed as antiproliferative activity measured as reduction in cell growth after 96 hrs by Cell-Titer Blue assay | Homo sapiens | 6 | ALA4406895 | cell-based format | Scientific Literature | |
5. | ALA4410583 | B | Binding affinity to human FRalpha/RFC/PCFT expressed in KB cells assessed as antiproliferative activity measured as reduction in cell growth after 96 hrs by Cell-Titer Blue assay | Homo sapiens | 6 | ALA4406895 | cell-based format | Scientific Literature | |
6. | ALA4410584 | F | Antiproliferative activity against human KB cells at 0.1 to 10000 nM after 96 hrs in presence of 60 uM adenosine by Cell-Titer blue assay | Homo sapiens | 4 | ALA4406895 | cell-based format | Scientific Literature | |
7. | ALA4410585 | F | Antiproliferative activity against human KB cells at 0.1 to 10000 nM after 96 hrs in presence of 10 uM thymidine by Cell-Titer blue assay | Homo sapiens | 4 | ALA4406895 | cell-based format | Scientific Literature | |
8. | ALA4410586 | F | Antiproliferative activity against human KB cells at 0.1 to 10000 nM after 96 hrs in presence of 130 uM glycine by Cell-Titer blue assay | Homo sapiens | 4 | ALA4406895 | cell-based format | Scientific Literature | |
9. | ALA4410587 | B | Inhibition of GAFTase in human KB cells assessed as inhibition of [14C(U)glycine incorporation into [14C]formyl GAR preincubated for 30 mins followed by [14C](U)glycine addition and measured after 16 hrs | Homo sapiens | 2 | ALA4406895 | cell-based format | Scientific Literature |