| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4399639 | B | Selectivity ratio of IC50 for human recombinant full length N-terminal his-tagged FABP5 expressed in Escherichia coli BL21 (DE3) to IC50 For human recombinant full length N-terminal his-tagged FABP4 expressed in Escherichia coli BL21 (DE3) | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 2. | ALA4399640 | A | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 30 to 60 uM incubated for 24 hrs by MTT assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4399641 | B | Displacement of 1,8-ANS from human recombinant full length N-terminal his-tagged FABP4 expressed in Escherichia coli BL21 (DE3) at 25 uM incubated for 3 mins by fluorescence based assay relative to control | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 4. | ALA4399642 | B | Displacement of 1,8-ANS from human recombinant full length N-terminal his-tagged FABP5 expressed in Escherichia coli BL21 (DE3) at 25 uM incubated for 3 mins by fluorescence based assay relative to control | Homo sapiens | 35 | assay format | Scientific Literature | ||
| 5. | ALA4399643 | B | Displacement of 1,8-ANS from human recombinant full length N-terminal his-tagged FABP4 expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by fluorescence based assay | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 6. | ALA4399644 | B | Displacement of 1,8-ANS from human recombinant full length N-terminal his-tagged FABP5 expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by fluorescence based assay | Homo sapiens | 23 | assay format | Scientific Literature | ||
| 7. | ALA4399645 | A | Displacement of 1,8-ANS from FABP3 (unknown origin) incubated for 3 mins by fluorescence based assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA4399646 | B | Selectivity ratio of IC50 for FABP3 (unknown origin) to IC50 for human recombinant full length N-terminal his-tagged FABP4 expressed in Escherichia coli BL21 (DE3) | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 9. | ALA4399647 | B | Selectivity ratio of IC50 for FABP3 (unknown origin) to IC50 for human recombinant full length N-terminal his-tagged FABP5 expressed in Escherichia coli BL21 (DE3) | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 10. | ALA4399648 | A | Cytotoxicity against mouse 3T3L1 cells assessed as reduction in cell viability at 30 to 60 uM incubated for 24 hrs by MTT assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA4399649 | B | Inhibition of FABP4 in mouse 3T3L1 cells assessed as inhibition of forskolin-stimulated lipolysis at 30 uM preincubated for 24 hrs followed by forskolin addition and measured after 2 hrs | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4399651 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced MCP-1 gene expression level at 30 uM preincubated for 12 hrs followed by LPS addition and measured after 6 hrs by qRT PCR analysis relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4399652 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha gene expression level at 30 uM preincubated for 12 hrs followed by LPS addition and measured after 6 hrs by qRT PCR analysis relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4399653 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-6 gene expression level at 30 uM preincubated for 12 hrs followed by LPS addition and measured after 6 hrs by qRT PCR analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4399654 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced COX-2 gene expression level at 30 uM preincubated for 12 hrs followed by LPS addition and measured after 6 hrs by qRT PCR analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4399655 | B | Inhibition of FABP4 in mouse RAW264.7 cells assessed as decrease in LPS-induced NF-kappaB phosphorylation at 30 to 60 uM preincubated for 12 hrs followed by LPS addition and measured after 10 mins by Western blot analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA4399656 | B | Inhibition of FABP4 in mouse RAW264.7 cells assessed as decrease in LPS-induced IKK phosphorylation at 30 to 60 uM preincubated for 12 hrs followed by LPS addition and measured after 10 mins by Western blot analysis | Mus musculus | 4 | cell-based format | Scientific Literature |
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