| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4328750 | A | Cytotoxicity in hepatocytes isolated from CYP activator dexamethasone-treated C57BL/6J mouse at 5 uM after 18 hrs by LDH assay relative to control | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA4328751 | T | Toxicity in liver microsomes isolated from CYP activator dexamethasone-treated Sprague-Dawley rat assessed as induction of mitochondrial permeability transition by measuring mitochondrial swelling at 50 uM measured after 30 mins in presence of NADPH | Rattus norvegicus | 7 | microsome format | Scientific Literature | ||
| 3. | ALA4328752 | T | Toxicity in liver microsomes isolated from CYP activator dexamethasone-treated Sprague-Dawley rat assessed as induction of mitochondrial permeability transition by measuring mitochondrial swelling at 50 uM measured after 30 mins in absence of NADPH | Rattus norvegicus | 7 | microsome format | Scientific Literature | ||
| 4. | ALA4328754 | B | Inhibition of human URAT1 expressed in HEK293 cells assessed as inhibition of [14C]-urate uptake at 10 uM after 2 mins by beta-scintillation counting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature |
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