# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4392025 | F | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7 measured after 72 hrs by SYBR Green 1 dye based fluorescence assay | Plasmodium falciparum | 48 | organism-based format | Scientific Literature | ||
2. | ALA4392027 | A | Half life in mouse liver microsomes at 1 uM measured after 30 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 11 | microsome format | Scientific Literature | ||
3. | ALA4392030 | B | Inhibition of recombinant human C-terminal His10-tagged BACE1 using Mca-SEVNLDAEFRK(Dpn)RR-NH2 as substrate measured after 60 mins by TR-FRET assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
4. | ALA4392031 | B | Inhibition of Plasmodium falciparum plasmepsin 2 using EDANS-CO-CH2-CH2-CO-ALERMFLSFP-Dap(DABCYL)OH as substrate measured after 60 mins by fluorescence assay | Plasmodium falciparum | 10 | single protein format | Scientific Literature | ||
5. | ALA4392032 | B | Inhibition of Plasmodium falciparum plasmepsin 4 using EDANS-CO-CH2-CH2-CO-ALERMFLSFP-Dap(DABCYL)OH as substrate measured after 60 mins by fluorescence assay | Plasmodium falciparum | 10 | single protein format | Scientific Literature | ||
6. | ALA4392036 | B | Inhibition of Tracer Red binding to human ERG expressed in membranes by fluorescence polarization assay | Homo sapiens | 10 | assay format | Scientific Literature | ||
7. | ALA4392037 | T | Selectivity ratio of IC50 for inhibition of Tracer Red binding to human ERG expressed in membranes to IC50 for chloroquine-sensitive Plasmodium falciparum 3D7 | 10 | assay format | Scientific Literature | |||
8. | ALA4392038 | A | Intrinsic clearance in mouse liver microsomes at 1 uM measured after 30 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 10 | microsome format | Scientific Literature |