# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4414743 | Binding | Inhibition of human 5-LO transfected in HEK293 cells coexpressing FLAP assessed as reduction in leukotriene formation at 1 uM using arachidonic acid as substrate preincubated for 5 mins followed by calcium ionophore A23187/arachidonic acid addition and measured after 15 mins by RP-HPLC analysis | Homo sapiens | 8 | ALA4414547 | cell-based format | Scientific Literature | |
2. | ALA4414748 | Functional | Antioxidant activity assessed as DPPH radical scavenging activity incubated for 30 mins under dark condition | 6 | ALA4414547 | assay format | Scientific Literature | ||
3. | ALA4414749 | Functional | Cytotoxicity against VHL-positive human RCC10 cells assessed as reduction in cell viability incubated for 4 days by XTT assay | Homo sapiens | 5 | ALA4414547 | cell-based format | Scientific Literature | |
4. | ALA4414751 | Functional | Cytotoxicity against VHL-deficient human RCC4 cells assessed as reduction in cell viability incubated for 4 days by XTT assay | Homo sapiens | 5 | ALA4414547 | cell-based format | Scientific Literature | |
5. | ALA4414752 | Functional | Cytotoxicity against VHL-positive human RCC4/VHL cells assessed as reduction in cell viability incubated for 4 days by XTT assay | Homo sapiens | 5 | ALA4414547 | cell-based format | Scientific Literature | |
6. | ALA4414753 | Functional | Cytotoxicity against VHL-deficient human RCC10 cells assessed as reduction in cell viability incubated for 4 days by XTT assay | Homo sapiens | 5 | ALA4414547 | cell-based format | Scientific Literature | |
7. | ALA4414754 | Functional | Cytotoxicity against VHL-deficient human 786-0 cells assessed as reduction in cell viability incubated for 4 days by XTT assay | Homo sapiens | 5 | ALA4414547 | cell-based format | Scientific Literature | |
8. | ALA4414755 | Functional | Cytotoxicity against VHL-positive human 786-0 cells assessed as reduction in cell viability incubated for 4 days by XTT assay | Homo sapiens | 5 | ALA4414547 | cell-based format | Scientific Literature |