# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4391164 | B | Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellman method | Homo sapiens | 9 | ALA4390652 | single protein format | Scientific Literature | |
2. | ALA4391165 | B | Inhibition of human serum BChE using BTCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellman's method | Homo sapiens | 9 | ALA4390652 | single protein format | Scientific Literature | |
3. | ALA4391166 | B | Selectivity index, ratio of IC50 for human serum BChE to IC50 for human recombinant AChE | Homo sapiens | 9 | ALA4390652 | protein format | Scientific Literature | |
4. | ALA4391167 | B | Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillation counting assay | Sus scrofa | 24 | ALA4390652 | assay format | Scientific Literature | |
5. | ALA4391168 | B | Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation counting assay | Homo sapiens | 24 | ALA4390652 | protein complex format | Scientific Literature | |
6. | ALA4391169 | A | Cytotoxicity against human HuH7 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
7. | ALA4391170 | A | Cytotoxicity against human Caco2 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
8. | ALA4391171 | A | Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
9. | ALA4391172 | A | Cytotoxicity against human HCT116 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
10. | ALA4391173 | A | Cytotoxicity against human PC3 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
11. | ALA4391174 | A | Cytotoxicity against human NCI-H727 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
12. | ALA4391175 | A | Cytotoxicity against human HaCaT cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
13. | ALA4391176 | A | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability at 100 uM incubated for 24 hrs by MTT assay relative to untreated cells | Homo sapiens | 3 | ALA4390652 | cell-based format | Scientific Literature | |
14. | ALA4391177 | A | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 3 | ALA4390652 | cell-based format | Scientific Literature | |
15. | ALA4391178 | A | Cytotoxicity against MDCK2-MDR1 cells assessed as reduction in cell viability at 75 uM incubated for 2 hrs by MTT assay | Canis lupus familiaris | 3 | ALA4390652 | cell-based format | Scientific Literature | |
16. | ALA4391179 | A | Apparent permeability across apical to basolateral side in MDCK2-MDR1 cells by HPLC analysis | Canis lupus familiaris | 4 | ALA4390652 | cell-based format | Scientific Literature | |
17. | ALA4391180 | A | Apparent permeability across basolateral to apical side in MDCK2-MDR1 cells by HPLC analysis | Canis lupus familiaris | 4 | ALA4390652 | cell-based format | Scientific Literature | |
18. | ALA4391181 | A | Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in MDCK2-MDR1 cells by HPLC analysis | Canis lupus familiaris | 4 | ALA4390652 | cell-based format | Scientific Literature |