# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4426961 | Binding | Inhibition of HIV1 protease using Abz-NleF*-6 as substrate preincubated for 5 to 10 mins followed by substrate addition measured after 1 hr by fluorometric assay | Human immunodeficiency virus 1 | 10 | ALA4425138 | single protein format | Scientific Literature | |
2. | ALA4426962 | Functional | Antiviral activity against HIV1 LA1 infected in human MT2 cells by MTT assay | Human immunodeficiency virus | 10 | ALA4425138 | organism-based format | Scientific Literature | |
3. | ALA4426963 | Functional | Antiviral activity against wild type HIV1 NL4-3 infected in human MT4 cells by p24 assay | Human immunodeficiency virus 1 | 4 | ALA4425138 | organism-based format | Scientific Literature | |
4. | ALA4426964 | Functional | Antiviral activity against multi-drug resistant HIV1B harboring protease L10I/L33I/M36I/M46I/F53L/K55R/I62V/L63P/A71V/G73S/V82A/L90M/I93L mutant infected in human MT4 cells by p24 assay | Human immunodeficiency virus 1 | 4 | ALA4425138 | organism-based format | Scientific Literature | |
5. | ALA4426965 | Functional | Antiviral activity against multi-drug resistant HIV1C harboring protease L10I/I15V/K20R/L24I/M36I/M46L/I54V/I62V/L63P/K70Q/V82A/L89M mutant infected in human MT4 cells by p24 assay | Human immunodeficiency virus 1 | 4 | ALA4425138 | organism-based format | Scientific Literature | |
6. | ALA4426966 | Functional | Antiviral activity against darunavir resistant HIV1 harboring protease L10I/I15V/K20R/L24I/V32I/M36I/M46L/L63P/A71T/V82A/L89M mutant at 20 passages infected in human MT4 cells by p24 assay | Human immunodeficiency virus 1 | 4 | ALA4425138 | organism-based format | Scientific Literature | |
7. | ALA4426967 | Unassigned | Ratio of IC50 for HIV1 LA1 to Ki for HIV1 protease | Human immunodeficiency virus 1 | 2 | ALA4425138 | assay format | Scientific Literature |