#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4334827	Binding	Reversible inhibition of human immunoproteasome beta 5i subunit assessed as recovery of enzyme activity at 45 nM using Suc-LLVY-AMC as substrate preincubated for 30 mins followed by 100-fold diluted substrate addition by rapid dilution assay relative to control	Homo sapiens	1	ALA4334435	single protein format	Scientific Literature
2.	ALA4334845	Functional	Inhibition of LPS-induced IL-8 production in human PBMC at 50 nM preincubated for 1 hr followed by LPS addition and measured after 24 hrs by cytometric bead array-based FACS analysis	Homo sapiens	1	ALA4334435	cell-based format	Scientific Literature
3.	ALA4334847	Functional	Inhibition of LPS-induced IL-1beta production in human PBMC at 50 nM preincubated for 1 hr followed by LPS addition and measured after 24 hrs by cytometric bead array-based FACS analysis	Homo sapiens	1	ALA4334435	cell-based format	Scientific Literature
4.	ALA4334849	Functional	Inhibition of LPS-induced IL-6 secretion in human PBMC at 50 nM preincubated for 1 hr followed by LPS addition and measured after 24 hrs by cytometric bead array-based FACS analysis	Homo sapiens	1	ALA4334435	cell-based format	Scientific Literature
5.	ALA4334850	Functional	Inhibition of LPS-induced IL-10 secretion in human PBMC at 50 nM preincubated for 1 hr followed by LPS addition and measured after 24 hrs by cytometric bead array-based FACS analysis	Homo sapiens	1	ALA4334435	cell-based format	Scientific Literature
6.	ALA4334856	Functional	Inhibition of LPS-induced IL-12p70 production in human PBMC at 50 nM preincubated for 1 hr followed by LPS addition and measured after 24 hrs by cytometric bead array-based FACS analysis	Homo sapiens	1	ALA4334435	cell-based format	Scientific Literature
7.	ALA4334857	Functional	Inhibition of LPS-induced TNFalpha production in human PBMC at 50 nM preincubated for 1 hr followed by LPS addition and measured after 24 hrs by cytometric bead array-based FACS analysis	Homo sapiens	1	ALA4334435	cell-based format	Scientific Literature
8.	ALA4704260	Binding	Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity	Homo sapiens	42	ALA4699588	single protein format	Scientific Literature
9.	ALA4704261	Binding	Inhibition of human constitutive 20S proteasome beta 5 chymotrypsin-like activity	Homo sapiens	42	ALA4699588	single protein format	Scientific Literature
10.	ALA4704262	Binding	Selectivity index, ratio of IC50 for inhibition of human constitutive 20S proteasome beta 5 chymotrypsin-like activity to IC50 for inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity	Homo sapiens	42	ALA4699588	assay format	Scientific Literature